WELLS LAB

The Wells Lab is devoted to understanding and modulating signaling processes in human cells through protein and small molecule design. We seek activators as well as inhibitors of signaling molecules, including proteases and kinases, and we use them to study the consequences of triggering specific nodes of signaling circuits. We are especially interested in the inter-protein circuitry of pathways involved in cell death and inflammation, and the intra-protein allosteric circuitry that governs how distant functional sites in one protein communicate... The Wells Lab is interested in designing proteins and small molecules that trigger cellular processes, in order to better understand and treat cancer and inflammation. Our research spans the multiple disciplines of chemical biology, biophysics, cell biology, molecular biology, enzymology, and proteomics. Our passion is to identify, activate, and inhibit critical signaling nodes to better understand how these drive responses such as cell..

Also known as: The Wells Lab

Primary location: San Francisco United States