CREAM

Current regulatory risk assessment of chemicals in Europe is based on the ratio between expected exposure in the environment and toxicity endpoints, e.g. hazard quotient, PNEC or TER. However, toxicity is usually determined at the level of individuals under laboratory conditions for a small number of standard test species. It remains unclear how well hazard quotients predict risks to populations and ecosystems, which are important environmental protection goals of current regulations in Europe. Since empirical approaches are too limited to solve this problem, mechanistic effect models are needed to make chemical risk assessment more ecologically relevant. To make this possible, CREAM is designed to (1) develop guidance for Good Modelling Practice which makes modelling more transparent, consistent, comprehensive, and reliable; (2) test and demonstrate the added value of models in a number of case studies; (3) train more researchers in both modelling and regulatory risk assessment so..

Registration numbers: HRB 4703 (W)

VAT numbers: DE 141507065

Primary location: Leipzig Germany