KOMP

The KOMP Repository is the official archive and distribution center for the Knockout Mouse Project (KOMP), a major 5-year trans-NIH initiative designed to generate null alleles in C57BL/6 embryonic stem (ES) cells for most genes not already available as knockout mice. Nearly 8500 genes are targeted for deletion, most in a conditional-ready format, by mutagenesis teams at CSD (Childrens Hospital of Oakland Research Institute, The Sanger Institute, and UC Davis) and at Regeneron, Inc. Here at the KOMP Repository at UC Davis and CHORI, you can obtain targeting vectors, ES cells, mice, and germplasm, as well as microinjection, genotyping, cryopreservation, breeding, and other services quickly and at reasonable cost to help you with your research project... The NHGRI and NCRR have recently funded the KOMP Mutagenesis Project and the KOMP Repository to create and characterize 312 unique mutant lines from targeted ESCs developed by the CHORI-Sanger-UC Davis and Regeneron consortium. This..

Also known as: KOMP Phenotyping Pilot