SYSTEMS BIOLOGY

Our main focus is directed towards protein expression design, cellular engineering and systems biology approaches for the production of functional proteins, virus like particles and infectious viruses. Our goals are influenza virus vaccine design in insect cells and mammalian cells as well as improving cell factories in general for production of functional proteins (e.g. enzymes) and DNA (DNA vaccine). Our core competence is design of expression cassettes and genetic engineering of production strains, needed for pharmaceutical and industrial biotechnology... In the past we have established a baculovirus surface display system which now serves to generate antibody-like proteins that specifically bind to chosen targets. This project is in collaboration with f-star GmbH... We have developed a large set of baculoviral vectors for influenza vaccine design and generation in insect and mammalian cells. For the past 10 years this research project has been funded by the FWF, Austria. During..

Also known as: Systems Biology Group

Primary location: Vienna Austria