ONCONET

OncoNET is an open-access, online resource developed by Kinexus Bioinformatics Corporation to foster cancer-related research in academia and industry. It features comprehensive information on the mutations and mRNA expression levels for about 3,000 genes in diverse types of human cancers. The mRNA expression data used in OncoNET was originally retrieved from the National Center for Biotechnology Information Gene Expression Omnibus (NCBI GEO), which serves as a repository of experimental gene microarray results submitted by diverse academic and industrial laboratories around the world. With the aid of our academic collaborators, Kinexus has normalized the data from hundreds of different gene microarray studies using a normalization protocol based on the identification of 60 genes that were commonly and highly expressed in all of the biological samples. To explore the mutation of human cancer-related genes, we relied primarily on the collection of data from the Wellcome Trust Sanger..

Also known as: Kinexus Bioinformatics Corporation