BARMADA LAB

The primary focus of the Barmada Laboratory is the molecular and pathologic overlap between amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease) and frontotemporal dementia (FTD). We are interested in the basic biology common to both disorders, and the cascade of events underpinning neural dysfunction, death and symptoms of disease. Our goal is to use this information to devise new and effective treatments for patients with ALS, FTD or both. To accomplish these objectives, we utilize a blend of technologies and disciplines, including molecular biology, neuroscience, fluorescence microscopy, and computer science to visualize neurodegeneration in real time and distinguish cause from effect... To identify and examine factors important for the survival and function of neurons in ALS and FTD, we employ automated fluorescence microscopy, a powerful technique enabling us follow thousands of neurons simultaneously in a longitudinal fashion. The method is equally applicable to mature..

Primary location: Ann Arbor United States