PROJECT DETOX

Project DETOX was launched in 2016 through the award of a 5-year Translation Grant through the Industrial Biotechnology Catalyst (Innovate UK, BBSRC, EPSRC). It is led from the Department of Biology at the University of York by Prof. Gavin H. Thomas with collaborators at the Universities of Nottingham, Sheffield, Exeter and Cambridge. Working with industrial partners Lucite, Ingenza and the CPI, the team aim to understand the physiological changes that microbes use to enable survival when exposed to bio-manufacturing chemicals that are toxic to them. DETOX solutions will then provide engineered chassis strains for its key partners for use in bioproduction to yield higher final titres of product - a problem that currently limits the financial viability of some processes... Product toxicity is one of the most serious barriers to commercialization of Industrial Biotechnology and Bio-Energy (IBBE). The DETOX project aims to provide the first ever systematic analysis of how chemicals..

Primary location: United Kingdom