CCFLOW - Key Persons
Doris Dallinger obtained her MSc and PhD degrees in the group of Professor Kappe at the University of Graz, Austria, on projects related to microwave chemistry and the high-throughput synthesis of biologically active heterocycles. After postdoctoral research work with a focus on microwave effects and scale-up studies she joined the Kappe Group at the University of Graz as Senior Scientist in 2011. Her main research interest and experience is related to reaction development and optimization by microwave technology and translation to continuous-flow conditions, in addition to evaluating green chemistry metrics and Life Cycle Assessment. She has published ca. 40 scientific papers and co-authored two books. Since 2018 she is Key Researcher at the Research Center Pharmaceutical Engineering Gmbh (RCPE).
Sándor B. Ötvös received his PhD in 2013 from the University of Szeged (Hungary) focusing on various projects related to continuous flow chemistry. He conducted postdoctoral research at the Hungarian Academy of Sciences (Szeged, Hungary) and then at the Institute of Chemical Research of Catalonia (ICIQ, Tarragona, Spain). In 2018, he joined the University of Graz, serving as a Senior PostDoc (Lise Meitner Fellowship, FWF) and later as a Principal Investigator within the framework of an FWF Stand-Alone Project. Currently he is a Principal Scientist at Research Center Pharmaceutical Engineering GmbH (RCPE). His research interests are focused on the combination of flow chemistry, catalysis, and photochemistry, with a special emphasis on the sustainable synthesis of active pharmaceutical ingredients and their advanced intermediates in aqueous slurries as reaction mixtures.
Job Titles:
- Member of the Technical and Administrative Staff
- Chemical Technician
Job Titles:
- Member of the Technical and Administrative Staff
- Laboratory Technician
Job Titles:
- Administrative Assistant
- Member of the Technical and Administrative Staff
Job Titles:
- Founding Editor
- Professor of Chemistry at the University
C. Oliver Kappe is Professor of Chemistry at the University of Graz (Austria) and Scientific Director of the Center for Continuous Flow Synthesis and Processing (CCFLOW) at the Research Center Pharmaceutical Engineering GmbH (RCPE). He received his diploma (1989) and his doctoral (1992) degrees in organic chemistry from the University of Graz where he worked with Gert Kollenz on cycloaddition and rearrangement reactions of acylketenes. After periods of postdoctoral research work on reactive intermediates and matrix isolation spectroscopy with Curt Wentrup at the University of Queensland in Brisbane, Australia (1993-1994) and on synthetic methodology/alkaloid synthesis with Albert Padwa at Emory University in Atlanta, USA (1994-1996), he moved back to the University of Graz in 1996 to start his independent academic career. He obtained his "Habilitation" in 1998 in organic chemistry and was appointed Associate Professor in 2000. Since 2011 he is Professor for "Technology of Organic Synthesis" (Organische Synthesetechnologie) at the Institute of Chemistry at the University of Graz. He has spent time as visiting scientist/professor at e.g. the Scripps Research Institute (La Jolla, USA, K. Barry Sharpless, 2003), the Toyko Institute of Technology (Toyko, Japan, T. Takahashi, 2008), the Sanford-Burnham Institute for Medical Research (Orlando, USA, 2010) and the Federal University of Rio de Janeiro (Rio de Janeiro, Brazil, 2013-2015).
Professor Kappe has an extensive general experience and a more than 30 year track record in synthetic organic chemistry, process intensification using batch microwave technology and flow chemistry/microreaction technology, communicated in >500 scientific publications (Web of Science, h-Index 90; Google Scholar h-Index 110; 2018 Clarivate Analytics Highly Cited Researcher). For the past 15 years the focus of his research has been directed towards flow chemistry/microreaction technology, encompassing a wide variety of synthetic transformations and experimental techniques. His research group is actively involved in projects dealing with API synthesis and sustainable manufacturing, employing a number of different enabling and process intensification technologies. For his innovative work in microwave chemistry he received the 2004 Prous Science Award from the European Federation for Medicinal Chemistry and the 2010 100.000 Houska Prize, in addition to a number of other awards. In 2015 he was named Fellow of the Royal Society of Chemistry. In 2018 is received the IUPAC-ThalesNano Award in Flow Chemistry.
C. Oliver Kappe is the Founding Editor (Editor-in-Chief from 2011-2018) of the Journal of Flow Chemistry (Springer) and a board member of the Flow Chemistry Society. He currently serves as an Editor for Chemistry-Methods (Wiley) and has been an Editor of the Journal QSAR and Combinatorial Sciences (Wiley-VCH, 2003-2007). In addition he serves on the Editorial/Advisory Boards of Green Chemistry, Reaction Chemistry & Engineering (RSC), Organic Process Research & Development (ACS), and Current Opinion in Green and Sustainable Chemistry (Elsevier). For several years he has been teaching courses on flow chemistry for Scientific Update.