SUNNYBROOK HEALTH SCIENCES CENTRE - Key Persons
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- Director, Sunnybrook Canadian Simulation Centre
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- Member of the Trainees and Research Staff
- Research Assistant ( Neuropsychology )
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- Research Manager With the Harquail Centre for Neuromodulation
- Research Manager, Neurodegenerative Diseases and HCN Business Manager
As a Research Manager with the Harquail Centre for Neuromodulation, Allison manages trials related to blood brain barrier opening for Alzheimer's and Parkinson's Disease as well as Neuroethics. She is also involved in financial management of HCN activities. Prior to clinical research, Allison performed intraoperative electrophysiology for neurosurgery and trauma patient populations at Sunnybrook. She holds a Master's degree in neuroimaging through the University of Toronto and Hospital for Sick Children. For Allison, the rewards of clinical trial management lie in enhancing the efficiency of multi-disciplinary teams and turning scientific discovery into innovative treatment options for patients.
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- Coordinator of the Brain Changes
Andrew Centen is the study coordinator of the Brain Changes in Sleep Apnea Study. He is also the study coordinator of the Ontario Sleep Health Study. Before starting in this role, Andrew opened and managed a private physiotherapy clinic and worked as a research coordinator in the Hurvitz Brain Sciences Research Program at Sunnybrook. He has completed a master of science in rehabilitation science at the University of Toronto and a bachelor of science in kinesiology at the University of Waterloo.
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- Research Manager for Neuromodulation
- Research Manager, Psychiatric Disorders
Anusha Baskaran is the Research Manager for Neuromodulation in Psychiatry at the Harquail Centre for Neuromodulation. Anusha completed her PhD in Clinical Neuroscience from Queen's University in collaboration with the Canadian Biomarker Integration Network in Depression (CAN-BIND) at the University Health Network, and is experienced in clinical trial management. Anusha's goal is to help improve treatment for psychiatric patients with treatment resistant illness by facilitating new developments of neuromodulation, and by maximizing the benefit of research collaborations and partnerships of growing networks.
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- Scientist, Toronto Rehabilitation Institute
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- Scientist, Physical Sciences, Hurvitz Brain Sciences Research Program
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- Member of the Trainees and Research Staff
- Coordinator ( Movement Disorders )
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- Member of the CPSR Management Team
- Director, Communications and Knowledge Translation
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- Member of the Trainees and Research Staff
- Master Student / Research Technician ( Oncology and Neurodegenerative Trials )
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- Member of the Trainees and Research Staff
- Grad Student
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- Member of the CPSR Management Team
- Scientific Director
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- Nuclear Medicine ) 416 - 480 - 6100 Ext. 2271
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- Site Leader, Ottawa Hospital Research Institute
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- Site Leader, University of Ottawa
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- Member of the Sunnybrook Sleep Clinic Team
Dr. Tandon is a respirologist in the Sunnybrook sleep clinic and head of the division of respirology. She is also an assistant professor in the division of respirology at the University of Toronto. Dr. Tandon's major interests are in sleep apnea and other sleep disorders, and the sleep-related complications of neuromuscular disease.
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- Vice - President, Education
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- Member of the Trainees and Research Staff
- Grad Student / Neurosurgery Resident
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- Co - Founding Leader / Co - Director
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- Co - Principal Investigator of the Brain Changes
- Senior Scientist at SRI
- Senior Scientist, Physical Sciences, Hurvitz Brain Sciences Research Program
Dr. MacIntosh is a co-principal investigator of the Brain Changes in Sleep Apnea Study. Dr. MacIntosh is a senior scientist at SRI in the Hurvitz Brain Sciences Research Program and a core member of the Heart and Stroke Foundation Canadian Partnership for Stroke Recovery. He holds an academic post as an associate professor in the department of medical biophysics at U of T, where he completed his PhD in 2006. The MacIntosh lab works on clinical translation of neuroimaging methods and tools, focusing primarily on blood flow-related measurements like arterial spin labeling and blood oxygenation level-dependent functional imaging techniques.
Job Titles:
- Member of the Sunnybrook Sleep Clinic Team
- Neurologist
- Scientist, Evaluative Clinical Sciences, Hurvitz Brain Sciences Research Program Head, Division of Neurology
Dr. Murray is a neurologist in the Sunnybrook sleep clinic and head of the division of neurology. He is also an affiliate scientist in the Hurvitz Brain Sciences research program at SRI and a professor in the division of neurology at U of T. Dr. Murray's major research interests are in neurological aspects of sleep and the relationship between sleep and behaviour. Some clinical conditions of interest include narcolepsy, rapid eye movement sleep behaviour disorder, restless legs syndrome and the effects of sleep and sleep disorders on other medical conditions.
Dr. Heyn is a neuroradiologist at Sunnybrook, an associate scientist in the Odette Cancer Research Program at SRI and an assistant professor in the department of medical imaging at U of T. The focus of Dr. Heyn's research is the application of molecular imaging techniques to the study, diagnosis and characterization of diseases of the central nervous system.
Dr. Clement Hamani is the Pre-Clinical Lead of the Harquail Centre for Neuromodulation, and a neurosurgeon and scientist at Sunnybrook Health Sciences Centre. Dr. Hamani received his medical degree from Escola Paulista de Medicina in São Paulo, Brazil in 1993, where he also received his PhD in Neurosciences. He completed a Research and Clinical Fellowship in Functional Neurosurgery at the Division of Neurosurgery at Toronto Western Hospital.
In 2008, Dr. Hamani joined the Centre for Addiction and Mental Health as a Research Associate and became an Assistant Professor at the University of Toronto, Division of Neurosurgery. In 2013, he won the Ohye Award, awarded by the World Society for Stereotactic and Functional Neurosurgery (WSSFN) to promote clinical research in stereotactic and functional neurosurgery. Dr. Hamani is Full Professor at the Division of Neurosurgery and a Board Member of the World Society for Stereotactic and Functional Neurosurgery. Dr. Hamani's research focuses on the treatment of movement disorders, epilepsy, and psychiatric disorders.
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- Scientist in Physical Sciences
Dr. David Goertz is a scientist in Physical Sciences and a principal investigator in SRI's focused ultrasound lab. His research focuses on understanding the basic behaviour of microbubble contrast agents in response to ultrasound to help develop new imaging techniques that will optimize the safety and efficacy of therapeutic applications. He is also studying the use of microbubbles to enhance drug delivery and efficacy in tumours by examining vascular flow response to therapeutically stimulated microbubbles, and how it can be exploited to promote drug uptake. He is an associate professor in the department of medical biophysics at the University of Toronto.
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- Scientist in the Odette Cancer Research Program at SRI
Dr. Elizabeth David is an affiliate scientist in the Odette Cancer Research Program at SRI and an interventional radiologist at Sunnybrook. She has led clinical trials at Sunnybrook evaluating MRI-guided high-intensity focused ultrasound for treatment of uterine fibroids, benign growths that can cause heavy bleeding, pain and infertility. She is an assistant professor in the department of medical imaging at the University of Toronto.
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- Director, Peters - Boyd Academy
Dr. Greg Czarnota is director of and senior scientist in the Odette Cancer Research Program at SRI. His research focus is on using ultrasound imaging and spectroscopy at conventional and high frequencies to detect apoptosis and other forms of cell death in response to chemotherapy and radiation therapy. He is also a radiation oncologist at Sunnybrook, where he led a pilot study that showed high-intensity focused ultrasound is a safe and feasible treatment for painful bone metastases. He is an associate professor in the departments of radiation oncology and medical biophysics at the University of Toronto.
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- Senior Scientist
- Senior Scientist, Biological Sciences, Hurvitz Brain Sciences Research Program
Dr. Isabelle Aubert is a senior scientist and neurobiologist in the Hurvitz Brain Sciences Research Program at SRI. Her expertise is in brain regeneration. She is head of the brain repair group at SRI, which is developing therapies to stop neurodegeneration and promote regeneration in Alzheimer's disease. She is evaluating drug therapies, immunotherapy, and gene and cell therapies for their potential in maintaining the health of the brain cells and inducing brain repair, toward restoring cognitive function. Working with Dr. Kullervo Hynynen, Aubert has demonstrated that focused ultrasound can be used to deliver therapies directly to the brain, bypassing the blood-brain barrier. She is also a professor in the department of laboratory medicine and pathobiology at the University of Toronto.
Dr. Jenny Rabin is the Neuropsychology Lead of the Harquail Centre for Neuromodulation and a Scientist at Sunnybrook Research Institute. Dr. Rabin completed her MA/PhD in Clinical Psychology at York University, with a specialization in Neuropsychology. She then went on to complete a joint clinical and research postdoctoral fellowship at Massachusetts General Hospital/Harvard Medical School.
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- ACLS Lead
- FRCPC, Director, Advanced Life Support Educator Program
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- Scientific Director
- Is Director
- Senior Scientist, Physical Sciences, Sunnybrook Research Institute
Dr. Kullervo Hynynen is director of and a senior scientist in Physical Sciences at Sunnybrook Research Institute (SRI) and the lead investigator of SRI's Centre for Research in Image-Guided Therapeutics. He has more than 30 years' experience developing clinical ultrasound therapy devices. Hynynen and his team have taken several ultrasound devices from ideas all the way to clinical testing. He is leading the development of the first low-intensity focused ultrasound brain device optimized to deliver therapies noninvasively past the blood-brain barrier into the human brain. Hynynen holds the Canada Research Chair in Imaging Systems and Image-Guided Therapy, and is a professor in the department of medical biophysics at the University of Toronto. He received the 2016 Visionary Award from the Focused Ultrasound Foundation. The award recognizes a person who has helped shape the future of focused ultrasound and whose dedication has advanced the field.
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- Director of Operations
- Research Manager
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- Member of the Sunnybrook Sleep Clinic Team
- Neurologist
Dr. Narayansingh is a neurologist in the Sunnybrook Health Sciences Centre sleep clinic. Dr. Narayansingh has a special interest in hypersomnias and narcolepsy, restless leg syndrome and other nocturnal limb movements, parasomnias, nocturnal seizures and sleep disorders associated with common neurological diseases.
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- Member of the Sunnybrook Sleep Clinic Team
- Assistant Professor, Department
- Neurologist
Mark Boulos, staff neurologist, Sunnybrook Health Sciences Centre; assistant professor, department of medicine, division of neurology, University of Toronto
Dr. Boulos is a neurologist in the Sunnybrook sleep clinic, an affiliate scientist in the Hurvitz Brain Sciences Research Program at SRI and an assistant professor in the division of neurology at U of T. His major research interests are in the intersection of sleep and cerebrovascular disease and ambulatory monitoring for sleep disorders.
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- Scientist in the Holland Bone
Dr. Meaghan O'Reilly is a scientist in the Holland Bone and Joint Research Program at SRI. Her research focus is on developing systems and methods to deliver, monitor and control ultrasound therapy. In particular, she has studied ways to map and control microbubble activity during targeted drug delivery in the brain. Her current research is on use of focused ultrasound to penetrate the blood-spinal cord barrier for treatment of spinal cord injury and disease. She is an assistant professor in the department of medical biophysics at the University of Toronto.
Dr. Michael Schwartz is a neurosurgeon and director of the neurotrauma program at Sunnybrook. His clinical and research interests focus on head injury and radiosurgery of brain tumors and vascular malformations. He is leading a clinical trial of MRI-guided transcranial focused ultrasound for treatment of medication-resistant movement disorders, including essential tremor, Parkinson's disease and Huntington's disease. He is a professor in the department of surgery at the University of Toronto.
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- Associate Scientist, Evaluative Clinical Sciences, Hurvitz Brain Sciences Research Program Head, Division of Geriatric Psychiatry
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- Clinical Director
- Director
- Director of Sunnybrook 's Harquail Centre for Neuromodulation
- Scientist at SRI
Dr. Nir Lipsman is a neurosurgeon and scientist at SRI. He helped lead Canada's first clinical trials of focused ultrasound in essential tremor and Parkinson's disease. He is developing trials investigating focused ultrasound in obsessive-compulsive disorder, depression and Alzheimer's disease. These first-in-human trials, done in collaboration with Dr. Kullervo Hynynen, represent the latest advances in MRI-guided focused ultrasound. His research focuses on the development of novel neuromodulation strategies, which target sites within the central nervous system using electrical stimulation or drugs, for neurological and psychiatric conditions that are difficult to treat.
Dr. Nir Lipsman is the Director of Sunnybrook's Harquail Centre for Neuromodulation (HCN), and the Clinical Director of Sunnybrook's Focused Ultrasound Centre of Excellence. Dr. Lipsman is a neurosurgeon and scientist at Sunnybrook Health Sciences Centre, and Assistant Professor of Surgery, and Director of Neurosurgery Residency Program at the University of Toronto. He completed his undergraduate degree at the University of Toronto followed by a medical degree at Queen's University, and a neurosurgical residency at the University of Toronto. During his residency, Dr. Lipsman completed his PhD investigating novel neuromodulation strategies in patients with treatment-resistant psychiatric and neurologic conditions. Dr. Lipsman's research focuses on the development of novel neuromodulation strategies for neurologic and psychiatric conditions that are difficult to treat. Over the last 10+ years, Dr. Lipsman has helped develop several Phase 1 to Phase 3 clinical trials of deep brain stimulation (DBS) and MR-guided focused ultrasound (FUS) in novel indications, including the world's first trial of DBS in chronic anorexia nervosa, and among the first published experiences of FUS for essential tremor. He has published over 150 peer-reviewed papers and book chapters, including in The Lancet, Lancet Neurology, Lancet Psychiatry, New England Journal of Medicine, and Neuron.
Dr. Peter Giacobbe is the Clinical Lead of the Harquail Centre for Neuromodulation and a psychiatrist in the Department of Psychiatry at Sunnybrook Health Sciences Centre. He is an Assistant Professor in the Department of Psychiatry at the University of Toronto, with appointments in the Division of Brain and Therapeutics and the Division of Geriatric Psychiatry. He completed medical school at the University of Western Ontario, followed by residency, fellowship training and graduate school at the University of Toronto. Dr. Giacobbe's clinical and research interests focus on the development and evaluation of novel direct-to-brain treatment strategies for individuals with treatment-resistant mood disorders. He has contributed to the 2009 & 2016 CANMAT Guidelines for the Management of Major Depressive Disorder and has published over 70 articles and book chapters on the topics of mood disorders and brain stimulation, including papers in the American Journal of Psychiatry, Biological Psychiatry, Brain Stimulation, CMAJ, Lancet, and Neuropsychopharmacology.
Job Titles:
- Co - Principal Investigator of the Brain Changes
- Director of the Hurvitz Brain Sciences Research Program of SRI
- Is Director
- Site Leader
Dr. Black is a co-principal investigator of the Brain Changes in Sleep Apnea Study. Dr. Black is the director of the Hurvitz Brain Sciences Research Program of SRI and a professor of neurology at U of T. She completed an MD at U of T and a fellowship in cognitive neurology at Western University. Dr. Black is the executive director of the Toronto Dementia Research Alliance, director of Sunnybrook's LC Campbell Cognitive Neurology Research Unit and site leader of the Heart and Stroke Foundation Canadian Partnership for Stroke Recovery. She serves on the executive committees of the Alzheimer's Association International Society to Advance Alzheimer Research, and the International Society for Vascular Behavioural and Cognitive Disorders. She is also a neurologist at Sunnybrook with a practice focusing on dementia, Alzheimer's disease, vascular cognitive impairment and stroke recovery. Her research focuses on the cognitive effects of stroke and stroke recovery, differential diagnoses of dementia, and use of neuroimaging techniques to elucidate brain-behaviour relationships in stroke and dementia.
Dr. Sandra Black is director of and senior scientist in the Hurvitz Brain Sciences Research Program at SRI. She is also a cognitive and stroke neurologist specializing in dementia and Alzheimer's disease. Her research focuses on the cognitive sequelae of stroke and stroke recovery, the differential diagnosis of dementia, the use of neuroimaging techniques to elucidate brain-behaviour relationships in stroke and dementia, and imaging-genetics correlations. Her work is highly influential. She has been a site investigator in more than 50 pharmaceutical clinical trials, and has led international trials in Alzheimer's and vascular dementia. She is the executive director of the Toronto Dementia Research Alliance. She is also a professor in the department of medicine at the University of Toronto, where she holds the Brill Chair in Neurology.
Dr. Sean Nestor is an assistant professor in the department of psychiatry at U of T with appointments in the Division of Brain and Therapeutics. He is a staff interventional psychiatrist at the Harquail Centre for Neuromodulation, Sunnybrook Health Sciences Centre, and an associate scientist at the Sunnybrook Research Institute, Evaluative Clinical Sciences Research Platform, Hurvitz Brain Sciences Program.
Dr. Sean Nestor trained in health sciences, biology and medical biophysics before completing his medical and doctoral studies at the University of Toronto, MD/PhD Program in 2016. He subsequently completed his residency in psychiatry at the University of Toronto in 2021 and Sean Nestor's work uses neuroimaging methods to investigate the neurobiological mechanisms that underpin neuromodulation treatments such as transcranial magnetic stimulation, electroconvulsive therapy, deep brain stimulation and magnetic resonance-guided focused ultrasound treatment in treatment resistant psychiatric disorders. His work also merges neuroimaging technologies to enhance the delivery of neuromodulation treatments in psychiatric disorders. He has received funding from CIHR, the Labatt Family Network for Research in Depression, Norris Scholars Award and the Sunnybrook Foundation. He has published peer reviewed articles on topics including mood disorders, neuroimaging, neurostimulation and dementia in several leading medical and scientific journals such as Brain, The American Journal of Psychiatry, Neuropsychopharmacology, Neuroimage, Human Brain Mapping, Alzheimer's & Dementia and Neurology.
Dr. Tobe is a nephrologist at Sunnybrook, an associate scientist in the Schulich Heart Research Program at SRI and a professor in the division of nephrology at the University of Toronto. Dr. Tobe's research focuses on enhancing the lives of people with or at risk of developing kidney disease by improving prevention, diagnosis and control of hypertension. Current projects include the relationship of stress and its management to hypertension, microalbuminuria and hypertension, and renal vascular disease.
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- Co - Founding Leader / Co - Director
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- Scientist at SRI
- Scientist, Evaluative Clinical Sciences, Hurvitz Brain Sciences Research Program
Dr. Swardfager is a scientist at SRI and an assistant professor in the department of pharmacology and toxicology at U of T. Dr. Swardfager's research focuses on cognitive symptoms, particularly in later life. Ongoing studies explore the neuroimmunological intersection between psychiatric and metabolic diseases as an avenue to discover biomarkers, elucidate vulnerability factors and suggest new treatments. The mechanisms by which cardiopulmonary fitness and exercise interventions counteract neurodegenerative processes are of particular interest.
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- Member of the Trainees and Research Staff
- Grad Student / Neurosurgery Resident
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- Director, Interprofessional & Academic Education
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- Research Physiotherapist, Sunnybrook
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- Manager, Library Services
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- Member of the CPSR Management Team
- Director, Research and Training Programs
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- Executive Assistant to Vice - President Education and Director Interprofessional & Academic Education Special Projects and IP Orientation Coordination
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- Member of the Board of Directors
- Scientific Advisor
- Director, Multi Magnetics Incorporated Associate Director, Lawson Health Research Institute
- Lawson Health Research Institute
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- Research Associate, Sunnybrook
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- Member of the Trainees and Research Staff
- Research Assistant ( Neuropsycholgy )
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- Member of the Board of Directors
- Professor, Departments of Medicine, Radiology, and Medical Biophysics, University of Western Ontario
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- Chairman
- Member of the Board of Directors
- Scientific Advisor
- Senior Scientist
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- Sciences Summer Student Research Program
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- Member of the Trainees and Research Staff
- Clinical Research Coordinator ( Oncology and Neurodegenerative Trials )
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- Senior Scientist, Biological Sciences, Hurvitz Brain Sciences Research Program
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- Scientist, Evaluative Clinical Sciences, Hurvitz Brain Sciences Research Program
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- Member of the CPSR Management Team
- Research Program Coordinator ( Currently on Mat - Leave )
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- Member of the Trainees and Research Staff
- Grad Student / Neurosurgery Resident
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- CEO
- Member of the CPSR Management Team
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- Senior Scientist, Evaluative Clinical Sciences, Hurvitz Brain Sciences Research Program
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- Site Leader, University of British Columbia
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- Assistant Professor, University of Waterloo
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- Administrative Assistant, Education Observers
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- Director, Practice - Based & Education Research
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- Site Leader, Toronto Rehabilitation Institute, University Health Network
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- Member of the Trainees and Research Staff
- Grad Student
Maheleth Llinas has more than 10 years of experience in clinical trials and regulatory compliance. She has collaborated on several Phase 1 - 4 human drug trials in previous Coordinator, Quality and Regulatory,, Assistant Medical Writer and Medical Affairs roles. In 2014, she joined the Sunnybrook Hospital research team where she managed the first ever pivotal trial in Canada for Magnetic Resonance Guided Focused Ultrasound (MRgFUS) for Essential Tremors. Since then, she has managed several studies involving invasive and non-invasive medical devices in brain related diseases such as: Alzheimer's disease, broad movement disorders, ALS and brain tumors. She is also oversees the day to day operations of HCN. Maheleth has a strong commitment to advancing medical research and passion for working in challenging therapeutic areas.
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- Member of the Board of Directors
- Scientist, Imaging Research Laboratories, Robarts Research Institute
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- Member of the Board of Directors
- Vice President - Equipment Operations, Communications and Power Industries Canada Inc
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- Site Leader, Memorial University of Newfoundland
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- Administrative Assistant, Postgraduate Medical Education
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- Health Professions Student Education Assistant
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- Coordinator, Management of Movement Disorders
Nadia completed a PhD in Behavioural Neuroscience at McMaster University. She began her research career investigating the impact of white matter injury on cognitive functioning in pediatric populations in the brain tumour and sickle cell programs at The Hospital for Sick Children. She joined Sunnybrook in 2015 and has supported several clinical trials in traumatic brain injury. Currently, Nadia oversees the Movement Disorders platform including MRI guided focused ultrasound (MRgFUS) trials for medication-refractory essential tremor and multiple sclerosis as well as the clinical MRgFUS treatments for these neurological disorders. Nadia's objective is to provide compassionate support in the care of patients with movement disorders and to continue expanding her expertise in focused ultrasound and neuromodulation.
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- Member of the Officer of the Board
- Officer of the Board
- Technical Director, Ontario Consortium for Cardiac Imaging
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- Scientist, Evaluative Clinical Sciences, Hurvtiz Brain Sciences Research Program
Richard Swartz, scientist, Evaluative Clinical Sciences, Hurvtiz Brain Sciences Research Program; director, stroke research unit neurology; director, University of Toronto Stroke Program
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- Research Fellow, Sunnybrook Research Institute
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- ALS Program Manager
- Manager, ALS Educator Program
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- Scientist, Evaluative Clinical Sciences, St. John 's Rehab Research Program
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- Member of the Trainees and Research Staff
- Grad Student
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- Site Leader, Hotchkiss Brain Institute at the University of Calgary
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- Member of the Board of Directors
- Professor, Department of Medical Imaging, University of Toronto
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- Research Fellow, Sunnybrook Research Institute
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- Administrative Assistant, Undergraduate Medical Education
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- Member of the Board of Directors
- Product Sales Manager, Cardiovascular Systems, GE Healthcare
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- Member of the Board of Directors
- Associate Professor, Department of Medicine and Radiology, University of Ottawa University of Ottawa Heart Institute
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- Financial Officer
- Member of the CPSR Management Team
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- Nursing Education Assistant
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- Member of the CPSR Management Team
- Research Program Coordinator
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- Professor, Department Chair, Department of Kinesiology, University of Waterloo
William McIlroy, professor, department chair, department of kinesiology, University of Waterloo
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- Associate Scientist, Evaluative Clinical Sciences, Hurvitz Brain Sciences Research Program