CABALETTA BIO

Cabaletta Bio is a clinical-stage biotechnology company focused on the discovery and development of engineered T cell therapies for autoimmune diseases. Our proprietary Cabaletta Approach to B cell Ablation (CABA®) platform is designed to provide durable, potentially curative, responses with one-time administration, with the possibility of eliminating the need for chronic immune suppressive therapies. We believe the CABA™ platform has potential applicability across a broad range of autoimmune diseases. It encompasses two strategies: the Chimeric Antigen Receptor T cells for Autoimmunity (CARTA) approach as well as our initial Chimeric AutoAntibody Receptor T (CAART) approach. Our lead CARTA candidate, CABA-201, is an investigational 4-1BB-containing CD19-CAR T cell therapy based on a clinically evaluated fully human CD19 binder. CABA-201 is currently under development for systemic lupus erythematosus, myositis, systemic sclerosis, generalized myasthenia gravis as well as other..

Also known as: Cabaletta, Cabaletta Bio, Inc.

Primary location: Philadelphia United States