IMMUNOGENESIS®

ImmunoGenesis is an immuno-oncology biopharmaceutical company re-envisioning "cold" tumor treatment. Our deliberate drug development strategy is based in the pathology of cold tumors. We are crafting sophisticated, science-driven immune therapies to transform cold tumors into hot tumors by targeting key mechanisms of immune resistance... IMGS-501, our STING‑mAb Immune Stimulating Antibody Conjugate (ISAC), builds on the novel PD‑L1/PD‑L2 dual‑specific inhibitor platform by conjugating a STING agonist to the antibody. This design combines a tumor‑specific transport vehicle in the PD‑L1/PD‑L2 dual‑specific antibody with a powerful immune agonist. We are developing ISAC to effectively and systemically transport the STING agonist to all tumor sites and to the right cells within the tumor microenvironment. This therapeutic advance pushes through an important barrier seen with traditional STING agonists, which consistently produce an effect only at the site of the intratumoral injection...

Also known as: ImmunoGenesis, Inc.

Primary location: Houston United States