GREENSTONE - Key Persons
Job Titles:
- HR MANAGER / OUTFORCE, LLP
Job Titles:
- Member of the SCIENTIFIC ADVISORY BOARD
- Distinguished Scientist
- SCIENTIFIC ADVISORY BOARD
Professor Axel Brunger is a distinguished scientist widely recognized for his remarkable contributions to the field of structural biology and the elucidation of molecular mechanisms underlying synaptic transmission. Professor Brunger's scientific career has been defined by his pioneering work in X-ray crystallography and electron microscopy, which have shed light on the intricate workings of biological macromolecules.
Axel's groundbreaking research focuses on the structure and function of proteins involved in neurotransmitter release, a fundamental process essential for neuronal communication. Through his innovative use of advanced imaging techniques, Axel has unraveled the three-dimensional structures of synaptic proteins, such as SNARE complexes, providing invaluable insights into the mechanisms of synaptic vesicle fusion and neurotransmitter release.
His seminal work has not only advanced our understanding of synaptic transmission but has also laid the foundation for the development of potential therapeutics targeting neurological disorders, including Parkinson's disease and epilepsy. Furthermore, Axel's contributions have had a profound impact on the field of structural biology, revolutionizing the field's techniques and methodologies.
Axel Brunger's outstanding achievements have earned him numerous accolades, including the prestigious Breakthrough Prize in Life Sciences in 2013. In addition to his groundbreaking research, he has played a pivotal role in mentoring and training young scientists, fostering a new generation of researchers in the field of structural biology.
With his relentless pursuit of scientific excellence and unwavering dedication to unraveling the intricacies of synaptic transmission, Axel continues to inspire and shape the field of structural biology, leaving an indelible mark on our understanding of the fundamental processes that govern the functioning of the brain.
Job Titles:
- Member of the SCIENTIFIC ADVISORY BOARD
- Scientist
- SCIENTIFIC ADVISORY BOARD
Professor Brian Kobilka is a renowned American scientist and Nobel laureate, celebrated for his groundbreaking contributions to the field of biochemistry and molecular biology. Kobilka's scientific journey has been characterized by his profound insights into the inner workings of G-protein-coupled receptors (GPCRs).
Kobilka's remarkable career gained international recognition when he successfully isolated and cloned the gene responsible for encoding the beta-adrenergic receptor, a crucial GPCR involved in cellular signaling. His meticulous work provided profound insights into how these receptors interact with various molecules, particularly hormones and drugs, which opened up new avenues for drug discovery and therapeutic interventions.
In 2012, Kobilka was awarded the Nobel Prize in Chemistry, jointly with Robert Lefkowitz, for their groundbreaking discoveries concerning GPCRs and their importance in cellular signaling. Their research revolutionized our understanding of these receptors and paved the way for the development of novel drugs targeting GPCRs, impacting various fields such as cardiology, neuroscience, and endocrinology.
Beyond his scientific achievements, Brian Kobilka is recognized for his dedication to teaching and mentoring future generations of scientists. He has been actively involved in academic institutions, including Stanford University, where he has made significant contributions to education and research.
Celine received her Bachelor's degree in biochemistry from the University of California, Los Angeles.
After, she worked with CRISPR-edited cancer lines before transitioning to the cardiovascular field at Dr. Joseph Wu's lab at the Stanford Cardiovascular Institute. Away from the lab, she enjoys traveling and trying out different desserts.
Job Titles:
- SENIOR RESEARCH ASSOCIATE
Chris graduated from Reed College in Portland, OR with a Bachelor's degree in Biochemistry and Molecular Biology. He then worked at the Stanford Cardiovascular Institute modeling genetic and cardiovascular diseases.
With a broad experience spanning the biotechnology sector, he has a deep interest in how we can provide better therapies at scale and reform the arduous process of drug discovery. A San Francisco Bay Area native, he can be found playing ultimate frisbee or trying new foods to eat.
David received his PhD in Biology and Biotechnology at Worcester Polytechnic Institute, where he investigated relationships between molecular signaling and cellular phenotypes in order to augment regenerative therapies. As a postdoctoral fellow in the Department of Surgery at Northwestern University, he subsequently studied therapeutic modalities to promote wound healing and suppress fibrosis using a combination of cellular and animal models, fostering burgeoning interest and expertise in basic pharmacology and drug repurposing.
David brings broad experience in regenerative medicine and humble fascination with the biomedical sciences to his role of Project Scientist at Greenstone Biosciences, where he hopes to facilitate the translation of scientific discovery into measurable, clinically significant patient benefit.
Job Titles:
- CO - FOUNDER
- Member of the Leadership Team
- Co - Founder of Greenstone Biosciences
Dr. Joseph C. Wu, MD, PhD, is a Co-Founder of Greenstone Biosciences and a distinguished scientist specializing in cardiology. As the Director of the Stanford Cardiovascular Institute and the Simon H. Stertzer, MD, Professor of Medicine and Radiology, he has established himself as a leading figure in the field. Dr. Wu obtained his MD. from Yale University and a PhD. in molecular pharmacology from UCLA, laying the foundation for his extensive contributions to the application of induced pluripotent stem cells (iPSCs) in disease modeling, drug discovery, and regenerative medicine. With over 500 peer-reviewed articles and an impressive H-index of 123, Dr. Wu's expertise is widely recognized, placing him among the top 0.1% highly cited researchers globally for the past five years. His exceptional achievements have garnered prestigious awards from the NIH and AHA, while his memberships in the NAI and NAM underscore his influential role in the scientific community.
Dr. Wu's remarkable career spans both academia and industry, with his co-founding role at Greenstone Biosciences exemplifying his commitment to translating scientific discoveries into tangible solutions. His groundbreaking research on iPSCs and their potential applications in regenerative medicine and drug development has paved the way for innovative approaches to tackle cardiovascular diseases.
With his vast publication record and exceptional H-index, Dr. Wu's contributions have made a lasting impact on the scientific community. His studies have shed light on the mechanisms of disease, provided valuable insights for developing targeted therapies, and accelerated progress in personalized medicine.
Beyond his research accolades, Dr. Wu's membership in prestigious institutions such as the National Academy of Inventors (NAI) and the National Academy of Medicine (NAM) reflects his influential role in shaping the future of healthcare and biomedical innovation.
As the incoming President of the American Heart Association, Dr. Wu is poised to lead the organization in its mission to combat heart disease and stroke, two leading causes of global mortality. His visionary leadership and expertise will undoubtedly contribute to advancing research, fostering collaborations, and advocating for policies that promote cardiovascular health.
Dr. Joseph C. Wu's groundbreaking research, entrepreneurial spirit, and leadership positions highlight his dedication to improving patient care and driving scientific progress. His work continues to pave the way for novel therapies, offering hope to individuals affected by cardiovascular diseases worldwide.
Dr. Zhang received his MD from Peking Union Medical College, Tsinghua University, where his work focused on improving the microenvironments of myocardial infarction. After graduation, Dr. Zhang completed his residency and cardiac fellowship in Fuwai Hospital.
He then pursued Postdoctoral training at Stanford University in Joseph Wu's lab. There he has developed antifibrotic therapies using human iPSC platforms, animal models, and in silico-based drug development.
Jade Chao - Chief Legal Officer, COO, Founder
Job Titles:
- CO - FOUNDER
- COO
- GENERAL COUNSEL
Jade is a dynamic and accomplished professional with a unique blend of expertise in health policy, law, big data, and biostatistics. She is also well versed in the areas of chemistry and human iPSC biology. With a passion for improving healthcare systems and advocating for social justice, Jade has made significant contributions to the field through her diverse roles and dedication to serving vulnerable populations. As a visionary leader and co-founder of Greenstone Biosciences, she has been instrumental in driving innovative solutions at the intersection of healthcare and technology. As a co-founder of Greenstone Biosciences, Jade has played a pivotal role in translating scientific discoveries into tangible solutions. Her visionary mindset, combined with her interdisciplinary expertise, drives the development of novel therapies, technologies, and strategies aimed at addressing unmet medical needs and improving healthcare delivery.
Armed with a Master's in Public Health (MPH) and a Juris Doctorate (JD) degree, Jade possesses a comprehensive understanding of the complexities surrounding public health policy and legal frameworks. Her academic background, coupled with her practical experience, allows her to approach complex issues with a multidisciplinary perspective.
Throughout her career, Jade has worked tirelessly to address health disparities and promote equitable access to healthcare. Her work has involved collaborating with governmental and non-profit organizations to develop and implement policies that improve health outcomes for marginalized communities. In 2020, Jade Chao authored a statewide resolution through the California State PTA to ban flavored tobacco products, a crucial initiative aimed at protecting youth from the harmful effects of tobacco use. Her advocacy work and dedication to promoting the health and well-being of communities have garnered recognition and support from the California State PTA.
She actively engages with community organizations and serves on boards that champion the rights and well-being of underserved populations. Her commitment to amplifying marginalized voices and promoting inclusivity has earned her recognition and respect within the field.
Her ability to bridge the gap between these two disciplines has allowed her to provide invaluable insights and guidance to organizations and policymakers seeking to create meaningful change.
Jade Chao's unwavering dedication to health policy, combined with her legal expertise, positions her as a catalyst for transformative progress. Through her advocacy, research, and leadership, she continues to make a significant impact on the lives of individuals and communities, striving towards a future where health equity and social justice are realized.
Jade enjoys gardening, calligraphy, and swimming.
Job Titles:
- Member of the SCIENTIFIC ADVISORY BOARD
- Scientist
Professor James Zou is an accomplished scientist and leading figure in the field of artificial intelligence and machine learning. Born with a passion for harnessing the power of data and computation to solve complex problems, Zou has made significant contributions to the areas of bioinformatics, computational biology, and healthcare.
Zou's research focuses on developing innovative machine learning algorithms and computational models to extract meaningful insights from vast and diverse datasets. He has pioneered novel approaches for analyzing genetic and biomedical data, with the aim of advancing our understanding of complex diseases and improving personalized medicine.
A sought-after expert in the field, Zou has published numerous influential papers, showcasing his expertise in topics such as deep learning, transfer learning, and fairness in machine learning. His groundbreaking work has not only contributed to the scientific community but has also found practical applications in healthcare, genetics, and precision medicine.
Beyond his research achievements, James Zou is known for his commitment to interdisciplinary collaboration and the ethical implications of artificial intelligence. He actively advocates for responsible and fair use of machine learning technology, particularly in sensitive domains like healthcare, where equity and privacy are paramount.
As an inspiring educator and mentor, Zou has played a pivotal role in shaping the next generation of AI researchers and practitioners. His dedication to fostering diversity and inclusivity in the field is reflected in his efforts to create an inclusive and supportive environment for underrepresented groups.
Jeremy received his PhD from the Department of Neuroscience at the University of Texas Southwestern Medical Center, studying the molecular mechanisms of neurotransmission. He then pursued postdoctoral training at Stanford University with Professor Axel Brunger. There he created a novel assay to examine functional and structural properties of synaptic vesicles ex vivo using a combination of fluorescence imaging and cryo-electron tomography. During this time, he co-developed software to analyze cryo-electron tomograms rapidly and in parallel. He continues to be an active contributor to the computational side of tomography data processing.
Besides his scientific interests, Jeremy is an avid outdoorsman who enjoys whitewater rafting, hiking and can't wait to introduce his son to these activities. He has completed multiple months-long hundreds of miles unsupported trips throughout his life. He also likes movies.
Lingyun earning her PhD in Molecular biology and Biochemistry from the University of California, Riverside. Later, she entered the Canary Center at Stanford to explore her passion in early cancer detection using in vitro blood biomarkers and protein engineering tools.
In addition to her primary research positions, she also worked as a laboratory manager for the CMB core of the Canary Center and later for Dr. Joseph Wu's lab at the Stanford Cardiovascular Institute.
Job Titles:
- Chairman of the BOARD of DIRECTORS
- Visionary Entrepreneur and Technology Investor
Lip-Bu Tan is a visionary entrepreneur and technology investor, renowned for his significant contributions to the semiconductor industry and his dedication to advancing artificial intelligence (AI) and transformative technologies. As the Founder and CEO of Walden International, a venture capital firm, and Cadence Design Systems, a leading electronic design automation company, Tan has played a pivotal role in shaping the landscape of the global tech industry.
With a strong educational background, including an M.S. in Nuclear Engineering from the Massachusetts Institute of Technology (MIT) and an MBA from the University of San Francisco, Tan possesses a rare combination of technical expertise and business acumen. His strategic insights and forward-thinking approach have led to the success of numerous companies in the semiconductor and AI sectors.
In addition to his accomplishments in the business world, Tan is deeply committed to philanthropy. Through his support for educational initiatives and entrepreneurship programs, he actively promotes the development of future leaders and the cultivation of innovation ecosystems worldwide.
Lip-Bu Tan's exceptional leadership, visionary mindset, and dedication to technological advancement have positioned him as a prominent figure in the global tech community. His influence and contributions continue to drive transformative change, shaping the future of industries and improving lives around the world.
Job Titles:
- DIRECTOR, PROJECT & PORTFOLIO STRATEGY
- Scientist With a
Mukhtar is an accomplished scientist with a Ph.D. from the University of Toronto, Department of Pharmaceutical Sciences, where he received exceptional training under the guidance of Professor Stephane Angers. His expertise lies in employing cutting-edge functional proteomics approaches to uncover novel non-canonical functions of heterotrimeric G proteins.
During his postdoctoral tenure at Vanderbilt University, Dr. Ahmed excelled under the mentorship of Professor Ian Macara and was ultimately promoted to the position of Research Assistant Professor. His remarkable contributions to the field involved utilizing advanced quantitative methods in cell biology, targeted proteomics, single molecule and membrane biophysics to unravel the intricate processes of polarized membrane trafficking and vesicle tethering in mammalian epithelial systems. Dr. Ahmed's research endeavors have been recognized and honored by prestigious institutions, including the Canadian Institutes of Health Research and the Natural Sciences and Engineering Research Council of Canada.
Notably, Dr. Ahmed's scientific journey also includes a pivotal role at the Howard Hughes Medical Institutes, where he was part of the pioneering team that established biomolecular protein complementation assays. This groundbreaking work showcases his ability to contribute to cutting-edge techniques and methodologies in the field.
Beyond his remarkable scientific achievements, Mukhtar nurtures a passion for music and is an avid collector of vinyl records. He finds solace in exploring arts and culture with like-minded individuals, fostering meaningful connections. In his leisure time, he rejuvenates by embarking on invigorating hikes through the woods with his loyal canine companion.
Job Titles:
- Scientist
- SENIOR SCIENTIST
Paul is a biomedical scientist with over a decade of research experience in disease modeling and translational medicine. Paul received his PhD in Integrative Molecular & Biomedical Sciences from Baylor College of Medicine and completed his postdoctoral training at Stanford University in the lab of Dr. Joseph Wu. He has been a prolific contributor to scientific literature and has received numerous awards and prestigious fellowships including the Ruth L. Kirschstein F31 and F32 NRSA Fellowships by the National Institutes of Health. In addition to his scientific interests, Paul enjoys playing volleyball, exploring new places, and writing short stories.
Rebecca graduated from the University of California, Irvine with a bachelor's degree in Pharmaceutical Sciences. Her education and previous work in aerosolized medicine and inhalation technology contributed to her interest in novel pharmaceutical strategies. Outside of work, Rebecca enjoys traveling and finding new coffee or tea spots.
Rabindra (Robin) received his PhD from the Department of Pharmaceutical Sciences at the University of Toronto and his graduate work focused on the mechanism of allosteric modulators at G-protein coupled receptors (GPCRs). After, he joined Stanford University as a post-doctoral and Dean's Fellow of the School of Medicine where he worked with Professor Brian Kobilka to understand how conformational changes in GPCRs determine their function. For this work, he was co-mentored by Professor Steven Chu to develop biophysical methods to assess GPCR function and this work was awarded with an interdisciplinary fellowship from the Stanford Neurosciences Institute. Robin enjoys playing tennis and biking and can be seen occasionally enjoying the beautiful biking trails in California.
Zach graduated from Brown University in Providence, Rhode Island with a Bachelor's Degree in Ecology and Evolutionary Biology. During his time there, he worked alongside Dr. Marc Tatar investigating renal fibrosis and mechanistic understandings of human neurodegenerative diseases. For this work, Zach received the Donald A. King Fellowship from the Huntington's Disease Society of America.
Following graduation, Zach moved to Hilo, Hawai'i where he served as researcher for the USDA Forest Service. During this time, Zach contributed to novel understandings of emergent forest diseases and early detection mechanisms. This work included groundbreaking discoveries for the use of remote sensing to detect early stage forest disease and inform forest management and planning.
Zach has always had a passion for elucidating rare disease mechanisms and improving the ways in which medicine is developed and delivered. He is excited to bring his expertise to the team to help achieve their collective goals. Outside of the lab, Zach can be found hiking, disc golfing, or playing video games with friends.