CHRISTOPH HOFSTETTER

In collaboration with Dr. Matthew Bruce at UW's Applied Physics Laboratory, we are implementing a novel Ultrafast Contrast-Enhanced Ultrasound platform to monitor hemodynamic changes after spinal cord injury with unprecedented temporal and spatial resolution. By combining a contrast agent with high frequency plane-wave ultrasound imaging, we are able to visualize tissue perfusion, as well as changes in vessel architecture and blood flow velocities. We believe that this technology will lead to significant improvements in the ability of physicians to identify tissue at risk for secondary damage after injury. Eventually this technology might lead to better functional outcomes for patients with acute spinal cord injury... Currently, we are engaged in studies aimed at altering the inflammatory response to spinal cord injury by targeting macrophages, promoting the formation of anti-inflammatory phenotypes over pro-inflammatory ones. We are also investigating the specific role that..

Primary location: University United States