CRI

The Children's Medical Center Research Institute at UT Southwestern (CRI) is addressing fundamental scientific questions related to the biological basis of disease. We seek breakthroughs that change scientific fields and yield new strategies for treating disease. Our ultimate goal is to cure people who would not be cured otherwise... CRI was established in 2011 as a joint venture built on the clinical expertise of Children's Health System of Texas and the scientific excellence of UT Southwestern (UTSW) Medical Center. Led by Sean J. Morrison, Ph.D., the Institute is home to an interdisciplinary group of scientists and physicians... NADP(H) not only supports the synthesis of building blocks required for producing new cells, but also helps cancer cells survive the oxidative stress they undergo when trying to spread through the body. Our knowledge of how NADPH is maintained and regulated in cancer cells is limited. A better understanding of how altered signaling pathways influence NADPH..

Primary location: Dallas United States