CHICAGO CENTER ON MUSCULOSKELETAL PAIN

Many hereditary connective tissue diseases are characterized by chronic pain. The Ehlers-Danlos Syndromes (EDS) are a group of rare heritable disorders resulting from defects in in genes encoding structural components of the extracellular matrix, in particular fibril-forming collagens types I, III, V, or molecules involved in the maturation, folding, secretion or supramolecular organization of these collagens. The syndromic presentation of joint hypermobility, skin hyperextensibility, abnormal scar formation and easy bruising is key to the diagnosis, but intractable pain is often the primary reason for these patients to seek medical help... This is the home page of the NIAMS P30 Chicago Center on Musculoskeletal Pain (C-COMP) directed by Dr. Anne-Marie Malfait. This is the home page of the NIAMS P30 Chicago Center on Musculoskeletal Pain (C-COMP) directed by Dr. Anne-Marie Malfait.