The Hotspotting the Overdose Epidemic Program (The Hotspotting Program), a partnership between the Staten Island Performing Provider System (SI PPS) and the MIT Sloan School Initiative for Health Systems, is a value-based care coordination program for Overdose (OD) and Opioid Use Disorder (OUD) treatment and prevention. The Hotspotting Program combines advanced predictive analytics, holistic person-centered medical and social needs support, and an innovative reimbursement paradigm.