ADHESION GPCR RESEARCH GROUP

Our research group focuses on the interactions and signaling of aGPCRs using ADGRG1/GPR56, ADGRE2/EMR2, ADGRD1/GPR133 and ADGRG5/GPR114. Currently, we are investigating the homo- and hetero-oligomerization in aGPCR family using Förster resonance energy transfer (FRET), bioluminescence resonance energy transfer (BRET); Spatial intensity distribution analysis (SpIDA) as well as fluorescence and bioluminescence complementation techniques.