JASANOFF LAB

Brain chemistry. Our group has a strong focus at the intersection of neuroscience and chemistry. We mean this in two senses: First, we make extensive use of methods from chemistry in our imaging probe development work, ranging from organic synthesis to bioconjugation and nanomaterials; we use rigorous chemical analyses and modeling to characterize probe function as well. Second, we study chemical processes in the brain that offer a counterpoint to more circuit-like conceptions of neural function... Molecular imaging. A core aim of the lab is to develop and apply unprecedented technology for molecular-level imaging in the nervous system. We focus largely on magnetic resonance imaging (MRI)-based methods, because MRI can provide whole-brain in vivo analogs of the powerful readouts optical imaging offers in invasive contexts. Some of our tools are compatible with other imaging techniques as well. Our laboratory has achieved a number of important milestones, which we seek to exploit and..

Primary location: Cambridge United States