THE SADLER LAB

We are a multidisciplinary group at the University of Edinburgh with a shared goal of developing sustainable, bio-based technologies to upcycle waste materials into useful chemicals. With a particular focus on plastic upcycling, we combine synthetic biology, protein discovery and engineering and organic chemistry to develop routes to chemicals currently produced from fossil fuels... Plastic upcycling offers tackles the plastic waste crisis whilst offering sustainable routes to chemicals currently produced from fossil fuels. We are expanding the scope of this emerging field by discovering new proteins and biocompatible chemistries that can be integrated into upcycling pathways, accessing more chemical space from waste feedstocks... We have demonstrated successful conversion of a plastic bottle into the flavour molecule vanillin. We're now excited to build on this and develop a range of new pathways to access high value chemicals using engineered microbes.

Primary location: Edinburgh United Kingdom