THE MAGEE LAB

We are currently examining how the various elements of a newly discovered form of synaptic plasticity (BTSP) are involved in producing learning-related changes in neuronal representations in several cortical areas (hippocampus, entorhinal cortex and barrel cortex)... We use intracellular and extracellular electrical recordings as well as 2-photon optical imaging techniques to record from both single neurons and populations in behaving mice and brain slices. We also employ various opto- and chemo-genetic techniques to manipulate circuits... Research Focus: Establish the circuit and cellular level mechanisms responsible for learning. The lab is interested in understanding how brains learn. Our long-term goal is to establish the circuit and cellular level mechanisms by which cortical representations are modified by experience and to determine how these learned representations improve behavior. We are currently examining how.

Primary location: Houston United States