HAEMOSTASIS

Molecular studies in Haemostasis are and will continue, to transform our approach to the investigation and management of individuals and their families with a wide variety of disorders of Haemostasis. This section of Practical-Haemostasis.com is designed to introduce you to molecular genetics as it relates to the inherited bleeding disorders. It is not a primer on genetics - there are some excellent sites on the internet that will do that. The internet also contains a number of mutational databases related to the inherited bleeding disorders and links to these are included... The methods for the various assays are covered throughout Practical-Haemostasis.com. It is important to remember that in many laboratories, factor assays are now fully automated. Historically coagulation tests were based on a visual assessment of the formation of a fibrin clot within a test tube. The time between initiation of clotting and the formation of the fibrin clot assessed visually, represented the..

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