CADASTER

CADASTER aims at providing the practical guidance to integrated risk assessment by carrying out a full hazard and risk assessment for chemicals belonging to four compound classes. A Decision Support System (DSS) will be developed that will be updated on a regular basis in order to accommodate and integrate the alternative methods mentioned above. Operational procedures will be developed, tested, and disseminated that guide a transparent evaluation of four classes of emerging chemicals, explicitly taking account of variability and uncertainty in data and in models. QSAR models will be developed and validated, also externally, according to the OECD principles for the validation of QSAR. The prediction of data for chemicals of the four selected classes, belonging to the applicability domain of the developed models, will be used for hazard and risk assessment, when experimental data are lacking. The main goal is to exemplify the integration of information, models and strategies for..