MICROARRAY RESEARCH LABORATORY

The Microarray Research Laboratory is a new facility founded in 2003 by EPA's Office of Pesticide Programs to conduct groundbreaking research in toxicogenomics. The laboratory is the state-of-art facility located at the Environmental Science Center, Fort Meade, Maryland... The Microarray Research Laboratory employs DNA microarray or Gene-chips to detect genotoxic effects of various antimicrobials on bacterial cell response. By using microarrays, the lab produces global gene expression profiles in pathogenic bacteria following exposure to antimicrobial agents. The global gene profiles are then analyzed to help us understand the mechanisms involved in toxicity and resistance so that we can design agents for specific pathogens, leaving minimal effects on other biospecies, including humans.