PHRAP

Phrap is a leading program for DNA sequence assembly. Phrap is routinely used in some of the largest sequencing projects in the Human Genome Sequencing Project and in the biotech industry... This page gives a brief description of Phred and Phrap. The Phred-Phrap programs were developed for use by automated scripts, and therefore do not have a graphical user interface. For scientists who prefer to use Phred and Phrap from a graphical user interface on OS X or Windows, we offer the sequence assembly and editing software CodonCode Aligner. CodonCode Aligner makes basecalling with Phred and sequence assembly with Phrap easy, and also offers functions for contig editing and mutation detection... Accurate consensus sequences. Phrap uses Phred's quality scores to determine highly accurate consensus sequences. Phrap examines all individual sequences at a given position, and generally uses the highest quality sequence to build the consensus - similar to the way scientists would correct..