CRESKO LAB

I am a geneticist who specializes in quantitative evolutionary genomics. Our laboratory studies the developmental genetic and genomic basis of evolution in natural populations. We use the threespine stickleback and zebrafish as the main animal models in the laboratory. We have produced some of the first work that has helped develop stickleback into a model for dissecting the genetic basis of natural variation. We have developed genomic tools (with the support of NIH) such as sequenced Restriction site Associated DNA (RAD) tags that help geneticists apply Next Generation Sequencing (NGS) technologies to biomedical and evolutionary genetic problems. These techniques allow for the efficient identification of thousands of single nucleotide polymorphisms (SNPs) throughout the genomes of models and non-model organisms. We produced the first SNP whole genome-scan for selection in the stickleback genome, and we developed novel Maximum Likelihood (ML) analytical tools for NGS data...

Primary location: Eugene United States