BRITT BALSER FOUNDATION

The foundation is named after 12-year-old Brittany Balser of Hilliard, who, after a 4-week fight with the disease in Children's Hospital in Columbus, Ohio, lost her life to TTP. Thrombotic thrombocytopenic purpura is a rare blood disease that afflicts females ages 20-50, but recently has afflicted younger girls ages 12 to 14... Our group has conducted several clinical studies to evaluate the efficacy of CSA, both as an adjunct to plasma exchange (PE) (1, 2) and alone in the treatment of idiopathic TTP(3). While these data suggest the efficacy of CSA in idiopathic TTP, questions regarding the mechanism of action and the risk of relapse after stopping CSA remain to be answered. Therapy with CSA continued after a patient has achieved a sustained (> 30 days) remission could be viewed as prophylactic, with a goal of preventing relapses (recurrence of TTP > 30 days after the last exchange) of TTP. This analysis is focused over the time period beginning 30 days after remission was achieved,..

Primary location: Westerville United States