BDF-C.COM

Vitiligo is a common chronic skin disease that is characterized by acquired depigmentation of skin. It affects different populations worldwide and affects different ages and both genders. Its prevalence in China is approximately 1%. Although vitiligo normally does not affect patient's general health, it often causes significant psychological burden to patient due to its severe cosmetic impact... Absence of functional melanocytes in the skin is believed to be the underlying mechanism of vitiligo. However, the exact pathogenesis of vitiligo still remains unclear and multiple hypotheses have been proposed including autoimmune mechanism, autocytotoxicity, neural hormone, autocrine dysfunction and genetic association... Although it is relatively straightforward to diagnose vitiligo, the treatment for vitiligo remains very challenging. There are several treatment options available so far including topical corticosteroid, topical calcineurin inhibitor, phototherapy, laser, surgical..