BAKER LAB - Key Persons
Abhishek is exploring how to create highly asymmetric protein assemblies with precise control over shape and size.
Adam is designing motions, mechanics, and kinetics of dynamic protein assemblies.
Aditya is designing de novo cytokines for autoimmune therapies
Alex is combining conformational dynamics with enzyme design
Alexis is a protein nanomachine designer and AI-based protein design researcher, exploring the field from first principles to translation.
Ali is designing phosphorylation-inducible heterodimers.
Andrew is developing deep learning models to design complexes containing both proteins and nucleic acids.
Andrew designs enzymes and develops methods for collecting and using large amounts of data to improve design outcomes.
Annika is designing transmembrane beta barrel proteins for small molecule sensing by improving deep learning methods
Arvind is working on the design of allosterically switchable enzymes, with the aim of building useful protein sensors and nanomachines.
Job Titles:
- Endowed Professor of Biochemistry, University of Washington School of Medicine
Avery is designing enzymes inspired by organocatalysts
Avi is designing new photosystems for artificial photosynthesis
Beau is designing de novo transcription factors to regulate gene expression.
Brian is trying to understand the forces that stick proteins together
Job Titles:
- Caixuan Is Doing Protein Design of IDP
Carl is designing enzymes to clean up forever chemicals
Job Titles:
- Visiting Professor from Chile
Cesar is a visiting professor from Chile, learning about AI-based protein design tools to generate new enzymes & enzymatic complexes
Chan is designing cytokine mimics to boost anti-cancer immunity with fewer side effects, activating only in tumor-specific environments
Christina is interested in designing immunomodulators to treat autoimmune diseases.
Chuanyun is designing modular transmembrane components for sensing, manipulating, and transporting.
Clara is designing proteins to edit the epigenome and stabilize blood vessels for therapeutics.
Cullen is designing protein motors that cycle between multiple well-defined states under power.
Job Titles:
- Principal Investigator
- Director, Institute for Protein Design
David is designing a modular protein toolkit to generate specific cell signaling outcomes.
Declan is designing enzymes for reactions not observed in Nature
Ella is designing proteins to modulate protein homeostasis.
Eric is developing and testing methods for antibody design.
Florence is designing light activated enzymes using noncanonical amino acid photosensitisers.
Giona is interested in designing a light-driven catalyst for phenol oxidation which could be further used in an artificial ETC.
Green is designing proteins to modulate cellular processes involved in cancer.
Hao is designing self-assembling protein filament nanomaterials
Harley is designing and characterizing proteins to control the formation of minerals
Isaac is developing methods to solve protein-protein interface design, enabling the creation of de novo protein therapeutics and cytokines
Jason Zhang is designing molecular tools to understand and manipulate cancer cell signaling.
Jonas is designing enzymes that catalyze new-to-nature reactions
Julia is making proteins that can specifically bind to peptide-MHC molecules for cancer immunotherapy.
Kathryn is designing proteins that undergo light-driven conformational change.
Kejia is on method development for binding peptides/intrinsically disordered regions, and functionalizing the binders.
Kiana is designing antibodies to advance biological therapeutic discovery
Kiera is designing enzymes for plastic degradation.
Kirsten is working on de novo protein and cellular cancer immunotherapies.
Kristin is designing protein sensing domains that can recognize phosphorylation.
Laura is designing peptide-MHC scaffolds to enable the understanding of peptide-specific disease associations.
Ljubica is solubilizing native membrane proteins using de novo protein design and making transmembrane proteins from scratch
Magnus is exploring the design of kinases and protein-based inhibitors to decode and manipulate cellular logic.
Marti is interested in modulating the immune response to vaccines through protein designed nanoparticles to generate long lasting response.
Meg is a BPSD graduate student in the King and Baker labs. She is working to improve vaccine efficacy using de novo protein design.
Michelin is using transmembrane beta-barrel proteins as nanopores to advance DNA and protein sequencing technologies.
Mohamad is designing proteins to understand and manipulate cell signaling networks
Nathan is designing protein binders to target cancer and increase our understanding of biology.
Nicole is optimizing yeast workflows to better identify useful de novo proteins
Paul is working on generative models for design of DNA-binding-proteins, with the eventual goal of optimizing for specificity.
Peik is designing redox enzymes and electron transport proteins for artificial photosynthesis
Rafi is working on deep learning methods for antibody structure prediction and design.
Raktim is developing methods for designing diverse Nucleic Acid binding proteins.
Ria is working on designing transmembrane beta barrels for biosensing applications
Riley is using both DNA-binder design and enzyme design to make de novo nucleases capable of cutting new recognition sites.
Rishabh is designing de novo protein binders to modulate cell signaling for various medical applications.
Riti is working on antibody design to accelerate biologic therapeutics R&D.
Rohith is developing neural networks for structure prediction and design.
Roman is designing novel enzymatic molecular motors.
Roni is working on designing new nanocage modalities for delivery.
Rose is designing proteins which undergo light-induced conformational change.
Ryan is designing proteins for purifying non-biological compounds of industrial interest
Ryan is training machine learning models specialized for predicting the structure and specificity of DNA-binding proteins.
Samir is designing mini-binders as potential therapeutics to combat infections associated with antibiotic-resistant bacteria.
Kenny is designing minibinder proteins to perform targeted protein degradation for novel therapeutic applications.
Seth is designing de novo (metallo)enzymes from transition state theozymes for diverse catalytic and photocatalytic applications.
Shayan is interested in designing binders to modulate protein homeostasis.
Shingo is designing asymmetric protein assembly aided by a peptide scaffold.
Stephanie is interested in therapies for autoimmune diseases.
Tim is making proteins that can be assembled sequentially (like solid phase synthesis with whole structural proteins)
Timo is designing acyltransferases to synthesize amide and ester bonds.
Tracy is working on developing bone-mimetic materials via hydroxyapatite mineralization proteins.
Wei is designing proteins to modulate gene expression
Xiangli is interested in designing protein binders to modulate the function of membrane proteins like GPCRs
Yang is designing proteins for tissue-specific drug delivery.
Yang is interested in designing protein and protein-adjacent bio-materials across different length scales (nano- to macro-scale).
Yuliya is working on the computational design of DNA binding proteins with a goal of developing de novo transcription factors.
Zhichun is developing deep learning methods to enhance the prediction of protein binding interactions
Zihao is interested in designing a synthetic proteome and an artificial cell