ORIGENDX

Personalized medicine tailored to the nuanced, and often unique, genetic, biochemical, psychological, exposure and behavioral features in individuals has evolved tremendously in recent years. The use of emerging technologies and the generation of large real-world datasets in the genomics, proteomics, imaging and other fields along with the use of artificial intelligence, including algorithms based machine learning, helps clinical professionals find better prevention and treatment options for complex disorders... Stress is a major risk factor for a large number of mental disorders. However, there are many differences between individuals and their response to stress resilience and vulnerability. The development of stress-related disorders is linked to a dysregulation of the stress responsive hypothalamic pituitary adrenal (HPA) axis, where the mineralocorticoid receptor (MR) and the glucocorticoid receptor (GR) play an important role. Other psychological and/or environmental factors,..