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Lancome's Resolution D-Contraxol Intensive Anti-Wrinkle Treatment Dermo-Crease Reducer ($68) was ten years in the making (one year for each word in its name?) and is based on the company's discovery that fibers within skin's fibroblast cells begin to cross as we climb into our thirties. So with each facial movement, the fibroblasts release or contract a little more slowly, and in time, lines are held in place permanently. Resolution's key ingredient, D-Contraxol, is a compound said to relax fibroblasts and smooth the skin. A network of nylon fibers acts as a wrinkle filler for immediate, visible results.