PTRNAPRED

Prediction of non-coding RNAs that are involved in post-transcriptional modification or DNA replication... The server aims for the prediction and classification of post-transcriptional RNA (ptRNA), which is a group of ncRNA that is involved in post-transcriptional modification or DNA replication. It can (i) predict, whether it will be ptRNA or non-ptRNA and (ii) predict the RNA class. Currently it can predict the 6 ptRNA families that exist in eukaryotes: snRNA, snoRNA, RNase P, RNase MRP, Y RNA and telomerase RNA. The tool uses an SVM based algorithm with sequence, secondary structure and thermo dynamical properties as input vectors. The prediction is as two-step approach. In the first step, a binary classifier distinguishes ptRNA from non-ptRNA. The next step contains multiclass classification, in which the tool identifies the ptRNA family that the sequence belongs to... snRNA: localized in the nucleus, where they are found in combination with proteins (snRNP). As part of the..