OHIO STATE UNIVERSITY - Key Persons
Job Titles:
- Graduate Research Associate, Chemical and Biomolecular Engineering / PhD Student, Chemical and Biomolecular Engineering
Job Titles:
- Graduate Teaching Associate, Chemical and Biomolecular Engineering / PhD Student, Chemical and Biomolecular Engineering
Professor Palmer's research interests encompass the development of novel hemoglobin-based oxygen carriers for a variety of applications in transfusion medicine and tissue engineering as oxygen therapeutics. His lab is also developing therapeutics for the detoxification of hemoglobin/heme/iron, non-heme based plasma substitutes, and monocyte/macrophage targeted drug delivery systems. He is author of more than 177 peer reviewed publications. Among others, he received the National Science Foundation Career Award, the Gaden award from the journal Biotechnology and Bioengineering, and the William W. Grimes Award for Excellence in Chemical Engineering from the American Institute of Chemical Engineers Minority Affairs Community. Prof. Palmer currently serves on the International Scientific Advisory Committee on Blood Substitutes, and recently completed a six year term as a member of the Bioengineering, Technology, and Surgical Sciences Study Section at the National Institutes of Health. He is a fellow of the American Institute for Medical and Biological Engineering, and the American Institute of Chemical Engineers. Palmer's research is supported by grants from the National Institutes of Health and the Department of Defense.
Job Titles:
- Endowed Chair in Chemical Engineering, Chemical and Biomolecular Engineering
Job Titles:
- Professor, Chemical and Biomolecular Engineering
David Wood received his undergraduate degree from Caltech in 1990 with a double major in Chemical Engineering and Molecular Biology. He has biopharmaceutical industry experience working on Neupogen® manufacturing at Amgen and downstream process development at Bristol Myers Squibb, and well as commodity scale bioprocess development at CP Kelco. Since receiving his PhD from Rensselaer Polytechnic Institute in 2000, professor Wood has developed groundbreaking new technologies in downstream bioprocessing, with a focus on self-cleaving affinity tag methods. His work has led to several issued patents in this area, and he is now an active consultant in the area of biosimilars development and intellectual property, as well as a co-founder of Protein Capture Science, a startup company commercializing his self-cleaving affinity tag technology.
Expertise
Novel and/or Non-chromatographic Recombinant Protein Purification; Biopharmaceutical Process Development; Protein Engineering; Molecular Cloning and Protein Expression; Metabolic Engineering; Biosensor Design based on Protein and Metabolic Engineering.
William G. Lowrie Department of
Chemical and Biomolecular Engineering
Job Titles:
- Chemistry and Biochemistry
A native of Memphis, Tennessee, Davita L. Watkins obtained her Bachelor of Science in Chemistry and Anthropology from Vanderbilt University in Nashville, Tennessee. After working briefly as a Lead Chemical Analyst for a bioanalytical company, she obtained a Ph.D. in Chemistry from the University of Memphis under the tutelage of Dr. Tomoko Fujiwara. As a doctoral candidate, she developed and established multi-step synthetic methods for a series of stimuli-responsive molecules and polymeric materials, demonstrating potential applications in phase transfer catalysis, catalytic control, and drug delivery. As a postdoctoral researcher at the University of Florida in Gainesville, Florida, with Dr. Ronald K. Castellano, she developed novel self-assembling organic materials for photovoltaic applications. In 2014, she began her independent academic career at the University of Mississippi. She joined the faculty at The Ohio State University in the Summer of 2022 as a tenured Associate Professor of Chemistry with a joint appointment in the Department of Chemical and Biomolecular Engineering. Her research interests focus on using noncovalent interactions to construct nanostructured polymeric materials. Her research has garnered numerous awards, such as the Oak Ridge Associated Universities (ORAU) Ralph E. Powe Award, a National Science Foundation CAREER Award, a Young Investigator Award from the Polymeric Materials: Science and Engineering (PMSE) Division branch of the American Chemical Society (ACS) and a Rising Star Award from ACS Women Chemists Committee (WCC).
Dr. Fernandes is developing new diagnostic histopathology methods for cancer detection. His approach combines DNA nanotechnology with polymer nanoparticles to create multiplexed erasable labels. He is co-advised by Dr. Jose Otero (Pathology).
Job Titles:
- Distinguished Professor of Engineering
Dr. W.S. Winston Ho is a Distinguished Professor of Engineering in the William G. Lowrie Department of Chemical and Biomolecular Engineering and the Department of Materials Science and Engineering at The Ohio State University. Before teaching for 22 years, he had 28 years of industrial R&D experience in membranes and separation processes, working for Allied Chemical, Xerox and Exxon, and serving as Senior Vice-President of Technology at Commodore Separation Technologies. He was elected to the National Academy of Engineering, USA in 2002 in recognition of his distinguished contributions to engineering. A New Jersey Inventor of the Year (1991), Dr. Ho holds more than 60 U.S. patents, generally with foreign counterparts, in membranes and separation processes. He received the 2006 Institute Award for Excellence in Industrial Gases Technology from the American Institute of Chemical Engineers (AIChE), and he was the 2007 recipient of Clarence G. Gerhold Award, from the AIChE Separations Division, one of the highest honors bestowed to those working on separations. He received the 2012 Lawrence B. Evans Award in Chemical Engineering Practice from AIChE. In 2014, he was elected to Academia Sinica, the highest form of academic recognition in the Republic of China in Taiwan. He obtained his B.S. degree from National Taiwan University and his M.S. and Ph.D. degrees from the University of Illinois at Urbana-Champaign, all in Chemical Engineering.
Expertise
Expertise
G. Sartori, W. S. W. Ho, and E. L. Stogryn, "Absorbent Composition Containing a Tertiary Amino Azabicyclic Alcohol and an Amine Salt and/or a Severely-Hindered Aminoacid and Process for the Absorption of H 2 S Using the Same", U. S. Patent 4,894,179 (1990).
Elizabeth Jergens Graduate Researcher Ms. Jergen's research is focused on the interface of DNA with nanomaterials. She is developing methods to cage nanoparticles using DNA nanostructures for applications in imaging, separations, and energy storage.
Mr. Khan's research is focused on developing new methods to manufacture nanoparticles toward commercial scales. HIs research is examining flash nanoprecipitation and electrohydrodynamic mixing reactors for high throughput nanoparticle manufacturing.
Job Titles:
- Graduate Research Associate, Chemical and Biomolecular Engineering / PhD Student, Chemical and Biomolecular Engineering
Job Titles:
- Chairman Emeritus, Chemical and Biomolecular Engineering
- Chairman in Chemical Engineering, Chemical and Biomolecular Engineering
Mr. Reardon is developing methods to purify and extract RNA molecules from dirty solutions. Such approaches could enhance single cell RNA genomics and improve sensitivity of infectious disease detection.
Professor Chalmers is currently researching intrinsic magnetization cell separation and immunomagnetic cell separation, cancer detection, and bioengineering.
Jessica Winter is a Distinguished Professor of Engineering in the William G. Lowrie Department of Chemical and Biomolecular Engineering and the Department of Biomedical Engineering and elected member of the American Institute of Chemical Engineers (AIChE) Board of Directors. She received her PhD in Chemical Engineering from the University of Texas at Austin in 2004, and completed a postdoctoral fellowship at the Center for Innovative Visual Rehabilitation at the Boston VA Hospital in 2006. Her research interests include nanoparticles for cancer imaging, diagnostics, and drug delivery; and cell migration in the brain tumor microenvironment. She is a co-founder and Chief Scientific Officer of Core Quantum Technologies, a company that markets nanoparticle reagents for cancer diagnostics. She was named TechColumbus Innovator of the Year, Columbus Business First 40 under 40, and Columbus Business First 20 People to Know in Technology. She has received the American Physical Society (APS) Five Sigma Award, American Chemical Society (ACS) Rising Star Award and the Engineering DesignNews Golden Mouse Trap Rising Star Award; she was named to Top 25 STEM professors in Ohio; and is a fellow of the AIChE, BMES, AAAS, AIMBE, the RSC, and senior member of the IEEE.
Expertise
Bionanotechnology, nanoparticles, quantum dots, magnetic nanoparticles, scalable nanomanufacturing, cancer, hydrogels, imaging, drug delivery, diagnostics, cell migration
Katelyn Swindle-Reilly, Ph.D., completed a B.S. in Chemical Engineering at Georgia Institute of Technology in 2004. She then received her M.S. in Chemical Engineering in 2006 and Ph.D. in Energy, Environmental, and Chemical Engineering in 2008 from Washington University in St. Louis. She completed postdoctoral training in Biomedical Engineering at Saint Louis University. After completing her postdoctoral training, Dr. Swindle-Reilly worked as a Senior Scientist at Rochal Industries LLC where she researched and developed several patented and FDA approved wound care products. She also designed manufacturing processes and preclinical studies for regulatory clearance of these new devices. She concurrently held an appointment as Adjunct Assistant Professor in Biomedical Engineering at The University of Texas at San Antonio from 2013-2015. She joined The Ohio State University in 2016, and holds appointments in Biomedical Engineering, Chemical and Biomolecular Engineering, and Ophthalmology and Visual Sciences.
Expertise
Dr. Swindle-Reilly's current research interests focus on the design of polymeric biomaterials for soft tissue repair and drug delivery with focused applications in ophthalmology and wound healing. She has expertise working with both polymeric and naturally-derived biomaterials, drug delivery, rheology and biomechanical testing, and tissue culture. Her research has spanned the fields of ophthalmology, wound healing, nerve tissue engineering, women's health, cancer, and drug delivery systems. Dr. Swindle-Reilly has experience taking research from idea to commercialized product, and holds several patents. She has entrepreneurial experience working on intellectual property protection, commercialization, and working with start-up companies. She serves as Chief Technology Officer of a startup company that licensed ocular drug delivery technologies from the university.
William G. Lowrie Department of
Chemical and Biomolecular Engineering
Job Titles:
- Graduate Research Associate, Chemical and Biomolecular Engineering / PhD Student, Chemical and Biomolecular Engineering
Job Titles:
- Graduate Research Associate, Chemical and Biomolecular Engineering / PhD Student, Chemical and Biomolecular Engineering
Mr. Lee is developing 3D models to study migration of glioblastoma brain cancer cells. His work is focused on investigating the effects of different tumor microenvironment cues on these migration patterns toward anti-invasion therapies.
Job Titles:
- Graduate Research Associate, Chemical and Biomolecular Engineering / PhD Student, Biomedical Engineering
R. E. Terry, N. N. Li, and W. S. W. Ho, "Extraction of Phenolic Compounds and Organic Acids by Liquid Membranes", J. Membr. Sci., 10, 305-323 (1982).
Job Titles:
- Professor of Chemical & Biomolecular Engineering
Yang is Professor of Chemical & Biomolecular Engineering (CBE), Food Science & Technology (FST), Biomedical Engineering, Molecular Genetics, Molecular, Cellular & Developmental Biology (MCDB) Program, and Biochemistry Graduate Program (OSBP) at The Ohio State University. Yang has been involved in bioprocessing research for more than 40 years, and has 12 related patents, some of which have been licensed to companies for commercial development. During his 36+ years at OSU, Yang has supervised many research projects on novel bioprocesses for value-added products from food and agricultural wastes, including metabolic engineering of clostridia and black yeast for biofuels and bio-based chemicals production, extractive fermentation for production of carboxylic acids, and novel bioreactor design and process scale up. His group pioneered in engineering clostridia for high-titer and high-yield butyric acid and n-butanol production from renewable biomass and CO 2. His research group also developed the first 3D cell culture system that can mimic in vivo tissue environment and be used reliably in high-throughput screening of chemicals for their embryotoxic potentials and/or as cancer drug targets. His current research involves biocatalysis, fermentation for value-added products from biomass and industrial wastes, metabolic engineering, stem cell and tissue engineering, and biochips for high-throughput cell-based assays and biodiagnostics. Dr. Yang has published more than 375 journal papers, proceeding articles, and book chapters in the field of bioprocess engineering, with over 17,500 total citations and an h-index of 77.
Job Titles:
- Graduate Research Associate, Chemical and Biomolecular Engineering / PhD Student, Chemical and Biomolecular Engineering
Job Titles:
- Member of the National Academy of Engineering
Job Titles:
- Graduate Research Associate, Chemical and Biomolecular Engineering / PhD Student, Chemical and Biomolecular Engineering
W. S. W. Ho, "Recent Developments on Membranes for Water Purification", Proceedings of 10th International Workshop on Drinking Water Quality Management and Treatment Technology, Taipei, Taiwan, June 1-2, 2004, Keynote Lecture, Paper No. B4-1, pp. 1-17. (invited).
W. S. W. Ho, "Removal and Recovery of Metals by Supported Liquid Membranes with Strip Dispersion", Proceedings of 2006 Workshop on Membrane Science and Technology, Chung-Li, Taiwan, June 8, 2006, Invited Lecture, Paper No. 5. (invited).
W. S. W. Ho, "Foreword", in A. K. Pabby, S. R. Wickramasinghe, K. K. Sirkar, and A.-M. Sastre, eds., Hollow Fiber Membrane Contactors: Module Fabrication, Design and Operation, and Potential Applications, CRC Press, Taylor & Francis Group, Boca Raton, FL, p. vii, https://bookshelf.vitalsource.com/#/books/9780429677441/cfi/6/12!/4/2/2/4@0:0 (online 2020) (2021). (invited)
W. S. W. Ho, G. Sartori, and E. L. Stogryn, "Absorbent Composition Containing a Severely-Hindered Amine Mixture with Amine Salts and/or Aminoacid Additives for the Absorption of H 2 S", U. S. Patent 4,961,873 (1990).
W. S. W. Ho, "Membranes, Methods of Making Membranes, and Methods of Separating Gases Using Membranes", U. S. Patent 8,277,932 (October 2, 2012).
W. S. W. Ho, W. Salim, and V. Vakharia, "Spiral-Wound Membrane Module for Gas Separations and Associated Methods", U. S. Provisional Patent Application No. 62/557,477 (filed September 12, 2017).
Job Titles:
- Distinguished Professor of Engineering, Chemical and Biomolecular Engineering
- Professor, Biomedical Engineering
Job Titles:
- Full Professor
- Professor, Chemical and Biomolecular Engineering / Professor, Biological Chemistry and Pharmacology
Dr. Xiaoguang "Margaret" Liu is a Full Professor in the Department of Chemical and Biomolecular Biological Engineering at The Ohio State University. Dr. Liu's research focuses on targeted anti-cancer therapy development, biomanufacturing and evaluations. She had worked in Biopharmaceutical and Biotechnology industries for almost seven years before joining academia. Dr. Liu accomplished her Ph.D. research in the Department of Chemical and Biomolecular at The Ohio State University in 2005.
Expertise
As a tenured Professor with over ten years of academic research experiences and seven years of biopharmaceutical industrial experiences, Dr. X. Margaret Liu has established multiple projects in different research fields such as targeted cancer therapy, drug delivery, innovative technologies development, biomanufacturing, and anti-cancer efficacy evaluation in various preclinical animal models. Her current research projects include antibody-drug conjugates to treat such as triple-negative breast cancer (TNBC), lung cancer and neuroendocrine cancer, mitochondria-targeted gene therapy to treat TNBC, lung cancer, and glioblastoma, targeted drug delivery, and bioprocessing and biomanufacturing. She is working on the development of combined mitochondrial gene therapy/chemotherapy, new monoclonal antibody development and engineering (humanization), dual-targeting and dual-payload antibody-drug conjugates, and new cancer therapeutic technologies. Her research also aims to move forward to translational studies and therapy commercialization.
William G. Lowrie Department of
Chemical and Biomolecular Engineering