PETAL NETWORK

The Clinical Trials Network for the Prevention and Early Treatment of Acute Lung Injury (PETAL Network) is a network of 12 Clinical Centers (CC) and 1 Clinical Coordinating Center (CCC) funded by the National Heart, Lung, and Blood Institute (NHLBI) to develop and conduct randomized controlled clinical trials to prevent or treat, and/or improve the outcome of patients who have, or who are at risk for, Acute Lung Injury (ALI) or Acute Respiratory Distress Syndrome (ARDS)... In August 2013, the National Heart, Lung, and Blood Institute (NHLBI) and National Institutes of Health (NIH) requested applications for a network that would "develop and conduct randomized controlled clinical trials to prevent, treat, and/or improve the outcomes of adult patients with or at risk for … ARDS." The PETAL Network's goals and guiding principles included: (1) conduct 3-5 phase III clinical trials of prevention or early treatment of patients with or at risk for ARDS. The goal was to enroll approximately..