MOVILEANU LAB
Updated 33 days ago
College of Arts and Science 201 Physics Building Syracuse, New York 13244-1130 USA
Liviu Movileanu's laboratory investigates a range of subjects from fundamental single-molecule and membrane biophysics to more applicative nanobiotechnology. His research team uses a broad spectrum of experimental techniques, from single-channel electrical recordings on planar lipid bilayers and proteoliposomes to the nanofabrication of silicon-based materials and protein engineering. The primary direction of this group is to design nanopore-based molecular probes for nucleic acids, proteins and their complexes with the interacting ligands... This research group employs various biological and synthetic nanopores to detect, explore and characterize biopolymers at high temporal and spatial resolution. The electrical measurements through a single nanopore illuminate the stochastic dynamics of individual molecules, such as their conformational fluctuations and interactions with other molecules, as well as the energetic requirements for their transition from one state to another. This..