OPRI - Key Persons

Job Titles:

• CCFP ( EM ) FCFP / Canada
• Home Expert Advisor

Job Titles:

• Global Research Collaboration Lead
• Singapore / Junior Research Associate

Amy graduated from the University of Manchester with a First-Class BSc (Hons) Degree in Biochemistry, where she accumulated experience in macromolecular recognition, genome regulation and protein dynamics. Whilst there, she also actively represented her field as a

Job Titles:

• Academic Assistant

Job Titles:

• United Kingdom / Honorary Senior Lecturer in Epidemiology

Andy joined OPRI in 2021, having previously been at the University of Birmingham since 2011 and the University of Exeter prior to that. He has over 20 years' experience of academic research within public health and health service research, developing research interests in respiratory disease, global health, health outcomes for older people and complex interventions. Andy has most recently collaborated with respiratory clinicians in Brazil, China, Georgia and North Macedonia on NIHR-funded studies relating to the diagnosis and management of COPD. Prior to this, he led the Birmingham COPD Cohort Study in the West Midlands, UK. Andy is skilled in epidemiology, research design, data analysis, quantitative research and statistics, and obtained his PhD in Medical Studies from University of Exeter in 2010.

Job Titles:

• Medical Writer

Antony Hardjojo is a Medical Writer with extensive expertise in clinical research and research publications primarily in the field of respiratory medicine. Antony was an in-house Medical Writer for OPRI before embarking on a journey as a Freelance Medical Writer. Currently, he continues to support OPRI as an honorary Academic Advisor.

Job Titles:

• Human Resources Lead

Job Titles:

• Medical Scientist and Research Fellow / United Kingdom

Celine joined OPCG in 2021, bringing with her a passion for clinical research and quality improvement. She graduated from University College London with a medical degree and an intercalated bachelor's degree in medical sciences with surgical sciences. As a medical student, she received the Ken Hobbs Prize in recognition of her academic performance and clinical research. Her work as a medical doctor in the UK's National Health Service further cultivated her enthusiasm for improving the care of broad patient populations via real-world research and quality improvement programmes. Celine also has experience in developing clinical trial publications as a medical writer. As a Medical Scientist at OPCG, Celine works mainly with the International Severe Asthma Registry (ISAR) team. She provides clinical input on research projects and publications, and collaborates with the team in improving the quality of ISAR's data.

Job Titles:

• Solicitor
• Commercial and Legal Director

Chris is a qualified solicitor and has been with OPRI since January 2017. Chris is our Commercial and Legal Director, bringing in his vast knowledge and experience gained from his time as a practising Finance & Projects solicitor within the UK. Chris originally attended the Sauder School of Business at University of British Columbia, Vancouver before transferring and qualifying from the University of Leeds with an LLB (Bachelor of Law Degree), before completing his Legal Practice Course at the University of Law, York. Chris completed his training contract with DLA Piper UK LLP. One of the big drivers behind Chris' move to OPRI was the ability to put his legal training into more specific practice in a commercially focused environment for a company doing ethically approved research in order to change patient outcomes globally. Within the company Chris sits on our senior management board and leads on client engagement, financial matters and legal contracting.

Job Titles:

• Home Expert Advisor
• Professor

Professor Halpin is Consultant Physician and Honorary Associate Professor in Respiratory Medicine at the Royal Devon and Exeter Hospital, Exeter, UK. He has a busy clinical practice and was Clinical lead 2003-16. He trained at Oxford University (first class honours); St Thomas Hospital Medical School, UK. He was awarded an MRC scholarship to undertake a D.Phil. in the Department of Human Anatomy, Oxford University, between his pre-clinical; clinical training. He trained in respiratory medicine at the Brompton Hospital, London. He is a Fellow of Royal College of Physicians, Member British Thoracic Society,European Respiratory Society and American Thoracic Society. His research is focused on clinical aspects of COPD and asthma and he has published over 140 peer reviewed papers. In 2018 he was elected as a Fellow of ERS in recognition of lifetime excellence and contributions to research, education and clinical leadership in respiratory medicine. He lectures frequently around the world on COPD and asthma. He is a member of the Board of Directors of the Global Initiative on Obstructive Lung Diseases (GOLD) and of the GOLD Science Committee. Until recently he was an Associate Editor of Thorax. He was the Chairman and Clinical Expert for the COPD Guideline Development Group of the National Institute of Clinical Excellence (NICE) in the UK. He was Respiratory Clinical Lead for the National Health Service (NHS) in the South West 2010-2015.

Job Titles:

• Founder and Head of the Observational and Pragmatic Research Institute

Professor David Price is founder and head of The Observational and Pragmatic Research Institute (Singapore), an independent, research-driven organisation established to cultivate initiatives, provide evidence and drive quality standards within the growing field of real-life, pragmatic and observational research. This dynamic organisation delivers pragmatic clinical trials and real-life database research across multiple geographies, including territories in the United States, Europe and the Asia-Pacific region, such as Singapore, South Korea, Taiwan, The Philippines, New Zealand, Australia, Japan and China. He is also head of Optimum Patient Care (Australia and UK), a science-based, social enterprise which focuses on disease registries and supporting care in primary and secondary care led by internationally recognised experts in all areas of respiratory medicine. Professor Price established the Optimum Patient Care Research Database (OPCRD; http://opcrd.co.uk/), one of the largest enhanced healthcare databases holding anonymous data from over 700 general practices and approximately 6.3 million patients in the UK. He currently leads the first International Severe Asthma Registry (ISAR; http://isaregistries.org/) by creating a consortium of world leaders at the forefront of severe asthma research from over 20 countries. His efforts have unified the severe asthma world by creating a vibrant space to exchange ideas and by standardising the data fields across countries, which is enabling data to be pooled and shared. Professor Price is Primary Care Respiratory Society Professor of Primary Care Respiratory Medicine at the University of Aberdeen (UK). He was awarded Fellow of ERS (FERS) in 2016. He is also a member of the World Health Organization (WHO) Allergic Rhinitis and its Impact on Asthma (ARIA) executive committee, the World Allergy Organization (WAO) Committee on Asthma, and the WAO Education Council. Professor Price was the founding president of the Respiratory Effectiveness Group (http://www.effectivenessevaluation.org/), a not-for-profit, investigator-led initiative which uses an international collaborative approach to explore the optimum role of real-life research in informing clinical guidelines and improving patient care. Professor Price completed his medical degree at Cambridge University in 1984. He was previously Affiliate Associate Professor in the Department of General Practice at the University of Adelaide, Australia and held an Honorary Chair at the University of East Anglia, UK. He is extensively involved in respiratory and allergy research; his areas of special interest are the ‘real-life' effectiveness and cost-effectiveness of interventions, clinical trial design, adherence, and patient attitudes to their disease. He has authored more than 490 peer-reviewed publications and is responsible for approximately US$50 million in research and clinical development grants. He is currently Editor-in-Chief of the journal Pragmatic and Observational Research and member of the editorial board of several respiratory journals, including The Lancet Respiratory Medicine.

Job Titles:

• Home Expert Advisor

Deborah joined OPCA in June 2021 following an international career in cardiology and respiratory nursing. Deborah has managed clinical teams in Saudi Arabia, United Kingdom and Australia. Deborah is passionate about improving outcomes for patients with respiratory disorders including asthma, COPD and interstitial lung disease. She has a research interest in Trachbronchomalacia and overlap disorders. Deborah completed her undergraduate degree at James Cook University in Queensland in 1998 and has recently completed post-graduate studies in clinical redesign through the University of Tasmania. She is currently undertaking a Master in Nurse Practitioner and a Master in Advanced clinical nursing both due for completion in 2022. During her time with OPCA, she has led on the Difficult to Treat Asthma Quality Improvement for Respiratory Physicians in the private practice and will continue to drive the difficult to treat asthma audit in primary care. During her time with OPCA, she has been instrumental in the establishment of quality standards in the DTT audit. Deborah is always striving to identify new research streams for respiratory patients. She is a Board member with Alpha1 Australia. She holds memberships with TSANZ, RCN, APNA, ERS and is on the spirometry steering committee for QHSTP.

Job Titles:

• Senior Data Analyst

Job Titles:

• Australia / Honorary Research Fellow

Dr Eve Denton is a Respiratory, Sleep and Allergy Physician with a special interest in severe asthma who combines clinical work and research at the Alfred and St Vincent's Hospitals in Melbourne. After finishing her M.B.B.S(Hons) in 2008 she completed Basic Physician Training at the Alfred Hospital and undertook Respiratory and Sleep Medicine training at the Alfred Hospital and St Vincent's Hospitals in Melbourne, qualifying as a Respiratory and Sleep Physician in 2016. During her basic and advanced training she completed a Masters of Public Health at Monash University focusing on epidemiology, biostatistics and clinical research and culminating in a minor thesis in lung cancer epidemiology. After finishing her specialty training she completed a two year clinical and research Fellowship at the Alfred Hospital focusing on Allergy and Asthma. She has an interest in inducible laryngreal obstruction and performs nasal endoscopy as well as assisting in setting up the Alfred Hospital Exercise-induced Laryngeal Obstruction (EILO) Service. She is currently undertaking a full time PhD in the area of Severe Asthma as well as her clinical duties and has published widely in peer reviewed journals.

Job Titles:

• Researcher

Heath worked as a Researcher at the School of Pharmacy at Keele University for 14 years. During this time, he gained extensive experience in managing and analysing a range of health-related data including longitudinal patient records contained within the Clinical Practice Research Datalink (CPRD). During his time working at Keele University, he obtained a PhD in Pharmacoepidemiology. Subsequently, Heath worked for 9 years in a number of health outcomes roles within the pharmaceutical industry. Heath joined OPRI as a Research Epidemiologist in 2018. Heath joined OPRI in 2018, having previously worked in GlaxoSmithKline Health Outcomes Department concentrating on respiratory medicines and diseases. Prior to this worked and studied at Keele University in the school of Pharmacy. He completed a PhD in 2000 in epidemiology. He has over 20 years of academic research experience working on analysis of a range of health-related data including real world databases including CPRD, THIN and OPCRD as well as other health resources such as hospital episodes and prescribing data.

Job Titles:

• Medical Scientist and Research Fellow / Hong Kong

Having graduated with a medical degree from the Chinese University of Hong Kong, Dr Jeffrey Chan is a clinical researcher in cardiology and general internal medicine. His research focuses on the epidemiology, prognostication, and detection of heart failure and other cardiovascular diseases, with special interest in echocardiography. He is also experienced in conducting systematic reviews and meta-analyses, and is an advocate for using trial sequential analyses in appropriate meta-analyses. He has published over 30 peer-reviewed original studies, meta-analyses and reviews in international medical journals. In addition to his engagements with OPRI, Dr Chan is currently a project lead and peer mentor at the Cardiovascular Analytics Group (Hong Kong - China - United Kingdom collaboration), and collaborates extensively with international investigators.

Job Titles:

• Associate Professor of Respiratory Medicine at the University of Ioannina
• Founder and Administrator of the Educational Facebook
• Home Expert Advisor

Dr. Kostikas is the founder and administrator of the educational Facebook group "What is New in Respiratory Medicine" with more than 5,500 members worldwide focusing on new developments in Respiratory Medicine. Dr. Kostikas has been involved in several posts of the European Respiratory Society (ERS) (e-Learning Resources Director, member of the HERMES examination committee for the European Diploma in Respiratory Medicine and member of the European Board for Accreditation for Pneumology). He worked for Novartis Pharma AG in Basel, Switzerland, between 2015 and 2018, as Medical Head Respiratory Region Europe, and subsequently WorldWide Brand Medical Director Respiratory, responsible for the inhaled and COPD Portfolio. Dr. Kostikas is currently an Associate Professor of Respiratory Medicine at the University of Ioannina and Head of the Respiratory Medicine Department of the University Hospital of Ioannina in Greece.

Job Titles:

• Co - Investigator
• Home Expert Advisor
• USA / Research Fellow

Dr. Margee Kerr is a sociologist with an interest in the behavioral and health sciences. After earning her PhD in 2009 from the University of Pittsburgh, she worked as a Senior Health Research Specialist for the Center for Health Equity Research and Promotion. There, she assisted Kerr additionally has served as a co-investigator on a research protocol focused on understanding

Job Titles:

• Home Expert Advisor
• Professor of Primary Care
• Senior Clinical Research Fellow at the Peninsula School of Medicine
• Senior Researcher at the Observational & Pragmatic Research Institute

Dr Rupert Jones is a Senior Clinical Research Fellow at the Peninsula School of Medicine, Plymouth. With a background of 30 years in general practice and a special interest in respiratory medicine, he continues to work in the Derriford hospital chest clinic as a locum consultant. He is the founding co-director of the Makerere University Lung Institute in College of Health Sciences in Kampala. Dr Rupert Jones is a senior researcher at the Observational & Pragmatic Research Institute in Singapore and has been involved in the design development of conduct and reporting of many database studies including pharmacoepidemiology, and the diagnosis and management of COPD and asthma. He is chair of the scientific committee of the Salford Lung study, which is the world's first pre-registration pragmatic randomised controlled trial (RCT) comparing Relvar with usual care in a real-life setting, published in The New England Journal of Medicine and The Lancet in 2017. He also established the National COPD Audit in UK with Prof Mike Roberts.

Job Titles:

• United Kingdom / Honorary Chief Investigator - PREVAIL - OPRI UK and Honorary Senior Lecturer in Primary Care Respiratory Medicine - OPRI SG

Katherine qualified from Leeds University in 2000. She originally did a Medicine Rotation acquiring her MRCP before settling into General Practice. She is a GP Partner in Bradford. Over the years Katherine has developed a keen interest in Respiratory medicine and is Respiratory Lead for West Yorkshire and Harrogate Health and Care Partnership. She also works extensively with the Primary Care Respiratory Society. Outside of work Katherine spends most of her time running around after her three children. She also enjoys baking, yoga and has recently rediscovered her love for singing and joined a choir.

Job Titles:

• United Kingdom / Research Fellow

Emma-Jane graduated from University of Birmingham with an MSc in Healthcare Management and is a graduate of the NHS Management Training Scheme. She is passionate about healthcare and health issues and has devoted more than 25 years to the field in both the NHS and private healthcare sectors. Her commitment to healthcare and designing innovative chronic care services to deliver clinical improvements have been recognised at national and international level. Emma-Jane is responsible for the delivery and growth of all Optimum Patient Care UK initiatives and collaborations.

Job Titles:

• Systems Analyst
• Australia / Junior Lecturer Systems Analytics
• Specialist

Fabio Botini is a Systems Analyst specialist with a decade of successful experience in Technology and Marketing. Fabio specialized in System Analysis and Design at Uniabeu University in Brazil in 2012 and regularly attends training sessions to showcase new tech trends, such as Health Informatics Specialization and patient analytics tools. A strong believer in the power of positive thinking in the workplace, Fabio regularly develops internal campaigns to assist employees and clients with effective connection techniques. His most recent achievement was an Advanced Diploma in Information Technology (2021). Fabio speaks Portuguese (Native), Spanish and English. Working at OPC Australia since January 2020, Fabio started his journey as a volunteer and was promoted to Junior Systems Analyst at the end of his volunteering period. He continues to contribute to OPRI research programs across a variety of roles.

Francis joined OPRI in 2013 after reading Medicine with an intercalated degree in Pathology at St Edmund's College, University of Cambridge. He has strong interest in development and delivery of pragmatic trials, and a desire to apply his medical knowledge in this field. Over the years he has worked to support implementation of multiple real-world trials, quality improvement programmes and clinical audits. He has experience with routinely collected healthcare data, quality improvement, health services and applied research. His broad experience provides him with clinical understanding of data and the ability to translate real-world data into research and actual healthcare improvement. He provides research implementation and clinical guidance to the organisation as a member of OPRI's Clinical Faculty. Francis is also the Data Custodian and Information Governance Lead for OPRI and the Optimum Patient Care (OPC) group. He oversees governance, data collection, linkage and optimisation the group's real-world databases for research and quality improvement. He hopes to continue to contribute to initiatives for improving real-life research and outcomes for patients.

Job Titles:

• Home Expert Advisor
• United Kingdom / Senior Research Fellow in Population Health / Professor of Clinical Epidemiology

Job Titles:

• United Kingdom / Honorary Research Fellow

Job Titles:

• Researcher

Job Titles:

• Data Quality Coordinator

Job Titles:

• General Practitioner and Assistant Professor at the Department of General Practice

Janwillem Kocks is a practising General Practitioner and Assistant Professor at the department of General Practice and Elderly Care Medicine at the University Medical Center Groningen, the Netherlands.

Job Titles:

• Academic Assistant

Job Titles:

• Research Fellow / United Kingdom

Kieran Lee is a PhD student in the Consciousness and Cognition Laboratory, University of Cambridge. His research is primarily focused on neurological and behavioural changes in patients with Obstructive Sleep Apnoea (OSA) before and after treatment, with other lines of work including OSA service accessibility improvement, personality traits related to drowsiness resilience and effects of opioid medication on OSA treatment. Previously Kieran has studied for a BSc in Psychology and the University of Stirling, before working in the Sleep Centre at Royal Papworth Hospital on the EU horizon 2020 project Track and Know. More recently Kieran has worked as project manager for OPRI on the ongoing MAGNIFY trial, assessing if a technological adherence support package can improve COPD outcomes. Kieran is a co-author of a paper published in the International Journal of Cartography, has published several conference abstracts from various UK and international conferences and has appeared on ITV's Evening News to discuss his research as part of the programmes sleep series.

Job Titles:

• Senior PA and Event Manager

Job Titles:

• Medical Scientist
• Senior Medical Data Scientist for ORTEC Health
• United Kingdom / Honorary Medical Scientist and Research Fellow

Marije van Melle is a medical scientist with a clinical and epidemiological background. She has a PhD in patient safety during patient transitions between GP and hospital, during which she developed measurement tools and a linked dataset between GP and Hospital medical records in the Netherlands. She has 10 years of experience as a scientist, both in the Netherlands and the UK (including at the University of Cambridge). She has experience with routinely collected data, data science and analysis, quality improvement, governance, and health services and applied research. Her broad experience provides her with clinical understanding of data and the ability to translate real-world data into research and actual healthcare improvement. For OPRI, Marije has been involved in several research projects, focussing on data science and translation, PROMs, QI and QI reports, and governance. She was involved in applying for linkage for OPCRD and the translation process of OPCRD into the OMOP Common Data Model. Additionally, she is part of the DSP team. After working as an employee, she currently is an independent consultant with OPRI. She leads the CLIPS (Code LIst Process Streamlining) team, improving valid measurement in the EMR for QI and Research purposes, and provides research and clinical guidance where needed. Additionally, Marije works as a senior medical data scientist for ORTEC Health (the Netherlands), bridging the triangle of medicine, math and ICT and developing new solutions for personalised medicine.

Job Titles:

• Expert

Nikolaos (Nikos) Papadopoulos is a world leading expert in allergy and asthma, through work on basic, translational and clinical aspects of the disease, as well as advocacy, pursued continuously for over 20 years. The focus of his research has been the role of infection, in particular rhinovirus (RV) infection, on asthma exacerbations and its interaction with atopy as keystone events of respiratory allergy pathophysiology as well as targets for treatment. Aspiring to develop impactful interventions at the clinical and public health domains, he has contributed to guidelines, real-life research and precision medicine. He did his medical and doctoral studies at the University of Athens, Greece and postdoctoral studies at the University of Southampton, UK, under the guidance of Sir Stephen Holgate and Sebastian Johnston. He then pursued an academic career in Athens, becoming Professor and Head of the Pediatric Allergy Department. In 2014 he was offered a Professorship at the University of Manchester and he is since running two active groups with overlapping but distinct research directions. From 2021, he has also been appointed Professor of Allergy, Immunity and Infection at OPRI, Singapore, to pursue real-life research in respiratory medicine. In the course of this career, he has identified some of the key mechanisms leading from common viral exposures to asthma exacerbations and persistence: his original studies in Southampton conclusively showed that RVs are capable of and infect the bronchial mucosa in humans (J Med Virol, 1999, J Infect Dis, 2000). They then induce local inflammation, initiating the exacerbation cascade (Clin Exp All, 2001), and synergize with house dust mite antigens (Clin Exp All, 2008). He has been the first to show that RVs can become cytotoxic (Respir Res, 2005) and induce viremia (AJRCCM, 2005). Explaining why atopic asthmatics are more susceptible to mild infectious agents than healthy individuals, he demonstrated already in 2002, a Th2 shifted, defective immune response to RV in asthma (Thorax 2002), followed by clinical proof of how atopy skews the duration of post-viral airway hyperresponsiveness (JACI 2005). A milestone finding was the capacity of RV to induce airway remodeling-associated growth factors with functional capacity (JACI 2006, CEA 2008, CTA 2012), suggesting that repeated viral infections may be the drivers of asthma persistence and the transition from wheeze to asthma. In more recent years, aspiring to address the challenges behind the generation of a vaccine for RV, he has identified a misdirected antibody response as a viral escape mechanism (FASEB J, 2012) and developed a chip capable of measuring subtype RV antibody responses (Nature Comm, 2018), with which he showed that while antibodies against type A and C RVs increase in parallel to the number of infections, there is little if any protection from subsequent events (AJRCCM, 2018). In the context of the EU project PreDicta (PAI, 2018), specific antisense inhibitors against RV infection (DNAzymes) were identified (JACI, 2019), while key molecular events were characterized, such as T-cell deviation induced by RV-induced IL33 (AJRCCM, 2014), the pivotal role of plasmacytoid dendritic cells in exacerbations (JACI 2018), and the functions of IL17 (Mucosal Immunol 2016), IFN-lamda (ERJ, 2017), IL-33 (Sci Rep, 2017), TGF-b (JACI 2017) and ILCs (Sci Rep, 2019). Working with RVs, he has improved molecular diagnosis (J Virol Meth, 1999), has observed, for the first time, their impact on acute bronchiolitis in infants (AJRCCM, 2002) and in pneumonia in older children (Clin Infect Dis, 2004), has contributed to the development of the first functional RV mouse model (J Gen Virol, 2003) and has generated models evaluating asthma drugs (CEA, 2006, CEA 2009). In parallel to his basic and translational research work he has remained clinically active, while he has been part of numerous efforts towards optimization of asthma treatment, proposing, among other, an algorithm for pediatric asthma phenotyping (Allergy, 2008), an algorithm for the use of molecular diagnosis to inform allergen immunotherapy for rhinitis and asthma (IAAI, 2013) and has led the 2012 International Consensus on Pediatric Asthma (Allergy, 2012). In the context of the EU project EARIP, he has proposed a stakeholder map to target advocacy actions for asthma research (ERJ, 2017), while he is leading efforts to recognize the value and standardize real-life research in asthma (CTA 2019, ERJ 2019). He has a passion for education, having supervised more than 20 PhDs, has organized over 100 educational events and has trained doctors in the clinic and researchers in the lab. He is invited speaker at international events more than 30 times a year. He has participated and/or led several European high-impact projects related to asthma or allergy, from FP5 all the way to Horizon2020. Notably, he joined BIOAIR (FP5, 2000-2004), longitudinally evaluating biomarkers of severe asthma, was among the team that designed and run GA2LEN (FP6, 2004-8), the Global Allergy & Asthma European Network, coordinated "PreDicta" (FP7, 2010-2016), evaluating the post-infectious immune reprogramming and its association with persistence and chronicity of asthma, and is currently the coordinator of the Horizon2020 Future & Emerging Technologies "CURE", constructing a ‘Eubiosis-Reistatement Therapy' for asthma (2017-2022). He has participated in and actively served many international societies, including committees of the ERS and EFA, but most notably EAACI, of which he was President 2013-2015 and the Respiratory Effectiveness Group (REG), of which he was President from 2018-2020. For his work he has received several international awards, among other, the EAACI Clemens von Pirquet Award (2019), the PhARF award (2010), the Klosterfrau International Award for Research in Pediatric Asthma (2003) and the ERS Annual Award for Pediatric Respiratory Research in Europe (2004). Overall, he has published over 500 papers, receiving more than 38000 citations and an h-index of 84 (Google Scholar). He is Editor-in-Chief of Frontiers in Allergy, Associate Editor of Clinical & Translational Allergy and member of the Editorial Boards of several scientific journals. His latest research direction has led to the establishment of a metagenomics laboratory in Manchester that is currently exploring the role of the respiratory virome and metagenome in asthma activity and exacerbations. In Athens he is evaluating potential interventions against rhinoviruses using microRNAs, while at the international front, he has organized PeARL (Pediatric Asthma in Real-Life), a think tank that aims to contribute in the everyday management of the disease and has evaluated the impact of the COVID pandemic on pediatric asthma patients (JACI:In Practice, 2020).

Job Titles:

• Administrative Assistant

Job Titles:

• Allergy Specialist
• Australia / Professor in Allergy
• Home Expert Advisor

Pete Smith is an Allergy Specialist based in Southport Qld. He did his RACP training Adelaide and a PhD in Molecular Immunology before working in London at the ICH and Great Ormond St in Food Allergy. He is a Professor in Clinical Medicine at Griffith University in Southport Qld, and is doing research in hypersensitivity, allergic rhinitis and food allergy. He is the Medical Director of Allergy Medical in Brisbane. He is a member of ASCIA, EAACI, AAAAI and WAO and has worked on expert committees with each of these organisations. He has been involved with the allergy working party of REG since 2013.

Job Titles:

• Researcher
• Singapore / Medical Scientist and Research Fellow

Rachel joined OPRI in 2019 following a clinical career in hospital geriatric medicine in the UK and Singapore. This led to an interest in pragmatic and real-world trials, and a desire to apply her clinical knowledge in this field. She is currently studying part-time for a MSc in Public Health with the University of London, which is due for completion in 2021. While at OPRI Rachel has provided clinical guidance and advice on quality improvement programmes and audit work related to COPD, asthma and heart failure. She has been significantly involved in the development of Quality Standards for clinical management of patients with modifiable high-risk COPD in the CONQUEST Quality Improvement programme, and in the development of the Global Operational Protocol to implement the CONQUEST programme.

Job Titles:

• New Zealand / Research Fellow

Job Titles:

• Quality and Publications Lead

Job Titles:

• Legal Counsel

Job Titles:

• Junior Medical Writer

Job Titles:

• Research & Operations Director

Victoria graduated from University of East Anglia with a first class BSc (Hons) degree in Psychology. Since this time Victoria has built a particular interest in the delivery of real-life and translational research globally. She led Optimum Patient Care, a growing social enterprise known throughout the world for its leadership in clinical services and collection of patient-reported outcomes for 5 years. Victoria is now responsible for the delivery and growth of all OPRI and OPC Global initiatives with experience in implementing internationally renowned services in respiratory medicine, including the iHARP initiative across 7 countries worldwide. She has contributed to a number of scientific papers and been fundamental in the successful delivery of several national initiatives, including the British Lung Foundation's Asthma Management Programme in the UK.

Job Titles:

• Chairman of Medical Statistics at the University of Exeter Medical School
• Home Expert Advisor
• Professor
• United Kingdom / Professor of Medical Statistics

Professor William Henley holds a Chair of Medical Statistics at the University of Exeter Medical School and is Head of the Health Statistics Group. He has more than twenty five years of experience as an applied statistician in industry and academia. Professor Henley received his undergraduate training in Mathematics at the University of Oxford. He has held postdoctoral positions in statistical epidemiology at the University of Oxford and the Animal Health Trust. Prior to joining the University of Exeter, he was Associate Professor (Reader) in Statistics in the Centre for Health and Environmental Statistics at Plymouth University. In 2010, he was seconded to the National Institute for Health Research (NIHR) Collaboration for Leadership in Applied Health Research and Care for the South West Peninsula (PenCLAHRC). He is a member of the South West Regional Funding Committee for the NHS Research for Patient Benefit Programme, and a member of the NIHR Stratified Medicine Working Group for using observational studies, registries and cohorts to design stratified trials. Professor Henley leads a programme of research on quasi-experimental analytic methods for conducting real-world evidence studies. Funded by the UK Medical Research Council Methodology Research Programme, his research group has developed extensions to the Prior Event Rate Ratio method, a promising approach to addressing hidden confounding in effectiveness studies using data from electronic medical records or large cohort studies. Professor Henley is Exeter Lead for the Clinical Practice Research Datalink (CPRD) and has been involved in the design, analysis and reporting of a wide range of pharmacoepidemiological studies using data from CPRD. He jointly leads a project funded by NIHR Research for Patient Benefit to evaluate whether statins modify the effectiveness of the influenza vaccine using data from primary care records. He is providing statistical leadership for several observational studies to stratify risk and assess interventions for COVID-19 and long COVID. He has authored more than 170 peer- reviewed publications and has a Google Scholar h-index of 50.