GLYSIGN

Glycomics is a technically difficult, highly specialised field and practitioners must be skilled to a high level in a wide range of analytical technologies. Also, large, complex multi-dimensional datasets impede interpretation. GlySign aims to train skilled glycomics specialists... Glycoproteins display glycan microheterogeneity, the analysis of which has been successfully tackled in a research setting, but remains a challenge in typical clinical chemistry labs. GlySign aims at the development of facile and robust procedures for high-resolution glycomics analysis in a clinical lab setting... GlySign aims at the advancement of medical glycomics, currently hampered by three main factors: Glycan microheterogeneity, lack of quality in biomarker validation, and the complexity of the glycomics analytical technology.

Primary location: Leiden Netherlands