SYSMITH CONSULTING

My career in preclinical safety assessments began more than 30 years ago at Charles River Laboratories in Montreal, known then as Bio-Research, where initially I learnt the regulatory aspects of drug development in QA, followed by several years as a toxicologist working as a study director... Bone Research has been at the heart of my career for more than 20 years starting in 1994 when the FDA issued guidelines for Osteoporosis drug testing. To meet the needs for the preclinical "Bone Quality" studies a unique department was created which today is recognized as the #1 laboratory world-wide for preclinical musculoskeletal research. The platform grew over the years to encompass various animal models, including bone healing, arthritis and muscle, in addition to screening models and short and long-term osteoporosis pharmacology and safety studies. As the Scientific Director for this endeavour, I acquired an in-depth knowledge of the core areas, including biochemical markers, bone..