REGENTS OF THE UNIVERSITY OF CALIFORNIA
Updated 1 day ago
- Age: 19 years
- ID: 35306765/89
Genentech Hall Room N272F 600 16th Street San Francisco, CA 94158-2517
Our group was founded in December 2006, when Dr. Kirichok moved from Harvard, where he was a postdoctoral fellow in the lab of Dr. David Clapham, to UCSF to establish his own lab. With the extraordinary help of the original lab members and generous support from the Department of Physiology at UCSF, the UCSF Program for Breakthrough Biomedical Research, an NIH Director New Innovator Award, the Larry L. Hillblom Foundation, and the Alfred P. Sloan Foundation, we initiated two pioneering research projects. The first project focused on understanding electrical signaling and transmembrane transport in mitochondria. It promised to significantly improve our understanding of basic mechanisms that control energy production, thermogenesis, cell aging, and cell death. The second project concentrated on electrical signaling at the sperm plasma membrane, and our aim was to understand the molecular mechanisms of male fertility and sperm-egg interaction. These two projects have resulted in important..