IVIG

Immunofluorescence and movement cytometry analyses revealed that EV71 could enter a pre-conventional dendritic cell (DC) human population in the disease sites. EGFP-EV71 via the respiratory path. Fluorescent sign tracing in cells from the pets contaminated with EGFP-EV71 demonstrated that EV71 proliferated mainly in the respiratory system epithelium as well as the connected lymphoid cells. Immunofluorescence and movement cytometry analyses exposed that EV71 could enter a pre-conventional dendritic cell (DC) human population in the disease sites. The viremia determined in the macaques contaminated by WT-EV71 or EGFP-EV71 was present actually in the artificial existence of a particular antibody against the disease. Our results claim that EV71 mainly proliferates in the respiratory system epithelium accompanied by following entry right into a pre-cDC human population of DCs. These cells are after that hijacked from the virus plus they could transmit the disease from regional sites to..