RACE-V

RACE-V is a network of researchers from Groningen, Maastricht and Leiden, financed by the Dutch Heart Foundation. Together, we are investigating how AF affects coagulation factors both in the blood and in atrial tissue and how these factors in turn alter the atrial tissue and lead to progression of AF... Translation to patients will be implemented in a registry of patients with early selfterminating AF. Using continuous rhythm monitoring combined with in-depth molecular-to-clinical phenotyping at the time of calamity (AF attack) and outside the time of calamity (sinus rhythm) including blood biomarkers of hypercoagulability, vascular disease, and fibrosis as well as electrocardiographic and imaging biomarkers, we will assess determinants of AF progression. In this way we aim to produce new diagnostic algorithms, electrical and biochemical biomarkers, and novel therapeutic modalities to prevent AF progression and its complications.