MEDINUP

The MedinUP is a research center of fundamental, translational-oriented and clinical pharmacologists aimed at fostering the development of better and safer medicines by exploring novel drug targets, unravelling new metabolic pathways and studying their interactions with living systems, grounded in pharmacogenomic and pharmacogenetic diversity, to boost pharmaceutical innovation and a personalized medicine... The MedInUP team of basic scientists, is grounded on a multidisciplinary team with specific interests on the prediction that cell-to-cell communication may be a key to control organ (dys)function, namely in what concerns (1) mechanosensing, pain and inflammation, (2) neuronal signalling, and (3) cardiovascular and renal homeostasis. Our aim is to identify purinome-based drug targets by manipulating mechanisms responsible for the release of ATP from excitable and non-excitable cells and the metabolic pathways leading to fine-tuning control of purinoceptors activation. The ultimate..

VAT numbers: B/04308/2020

Primary location: Porto Portugal