PRERAU LAB

We have developed a new approach to creating individualized electroencephalogram (EEG) fingerprints of brain activity during sleep, which can be used to identify biomarkers of neurological health and disease. We first identify tens of thousands of short, spindle-like EEG waveforms called time-frequency peaks (TF-peaks) across a night of sleep. Then, we create visual summaries of brain state by characterizing the activity of TF-peaks as a function of sleep depth and also cortical timing, called SO-power and SO-phase histograms. These summaries, like fingerprints, appear to be unique to individuals yet consistent night to night, providing a highly informative new visualization technique and powerful basis for understanding neurological health and disease... Obstructive sleep apnea (OSA) affects at least 10% of the population and is associated with numerous comorbidities. While OSA is a complex dynamic process, the main metric for diagnosing OSA, the apnea-hypopnea index (AHI), reduces..

Also known as: Prerau