EBV

EBV is one of the most common human viruses and is associated with more than a dozen malignancies in both hematological and solid tumors. 8 EBV infects 90% of people before adulthood across the world. 9... EBV primarily infects B cells. Primary EBV infection usually occurs prior to adulthood through exposure to saliva or other fluids of an infected individual and results in either asymptomatic infection or symptomatic mononucleosis. 9 Following primary infection, EBV establishes a latent infection that persists within memory B cells at low levels, which results in a lifelong infection that the immune system can usually control but cannot clear. 9 In immunocompetent individuals, EBV infection is controlled by a strong immune response of virus-specific and nonspecific T cells that eliminate the majority of EBV-infected B cells. 10... Epstein-Barr virus positive post-transplant lymphoproliferative disease (EBV+ PTLD) is a rare, acute, and potentially life-threatening lymphoma that..

Also known as: EBV+ PTLD

Primary location: South San Francisco United States