WASHINGTON UNIVERSITY IN ST. LOUIS

The goal of the Karch lab is to understand the molecular drivers of Alzheimer's disease, frontotemporal dementia, and other neurodegenerative disease. To do this, we use functional genomics along side stem cell and mouse models. The Karch lab has developed a somatic and stem cell collection containing deeply clinically characterized cell lines from individuals carrying genetic drivers of Alzheimer's disease, frontotemporal dementia, amyotrophic lateral sclerosis and Parkinson's disease. These cells are used to develop novel tools to interrogate mechanisms of neurodegenerative disease. Additionally, the Karch lab couples high-throughput transcriptomics and proteomics in stem cells and human brain tissues to identify disease signatures and to understand protein kinetics in disease... Welcome to the Karch Lab! Our Scientific Mission The goal of the Karch lab is to understand the molecular drivers of Alzheimer's disea..... Our goal is to perform cutting-edge research to understand and..

Also known as: Karch Lab

Primary location: St. Louis United States