CASCADE BIOTECHNOLOGY

Cascade Biotechnology is developing therapeutics that use the body's complement system to attack diseases and disorders such as Alzheimer's disease (AD), schizophrenia (SZ), myasthenia gravis (MG), Neuromyelitis Optica (NMO), cancer, adult macular degeneration (ADM), blood diseases such as paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS) and others... At Cascade, we are developing a gene therapy approach to these common and deadly renal inflammatory diseases... Cascade has state of the art in silico protein modeling and analysis technology to create superior biologics based on complement proteins. Our in silico platform uses advanced immunogenicity prediction using massive informational libraries of immunogenic motifs. We have a full BL2 cell culture facility to create and test our therapeutic proteins. Cascade has developed novel purified protein, cell-based and ex vivo model systems to test activity and predict bioavailability. We are using..

Also known as: Cascade, Cascade Biotechnology, Inc.

Primary location: Monmouth Junction United States