FRANCIS MEDICAL - Key Persons

Job Titles:

• Executive
• CEO, Fogarty Innovation

Andrew Cleeland is a seasoned executive with 30+ years in the medical device industry in both the private and public sectors. He is on the boards of Saluda Medical, Zenflow, Inc. (chairman), MMI S.p.A. (chairman), and NXT Biomedical and holds advisory positions at two top-tier VCs: Longitude Capital and Arboretum Ventures. Andrew also serves on multiple industry initiatives including the UCSF-Stanford Pediatric Device Consortium; the Medical Device Innovation Consortium; and the Singapore government's Biomedical Research Council (BMRC). Andrew is passionate about healthcare and a champion of innovators and innovation in the medical technology field.

Job Titles:

• Chairman of the Board

Mr. de Bruin brings more than 35 years of global healthcare industry experience spanning the biopharmaceutical, medical device and in-vitro diagnostics markets. Prior to his retirement in 2004 as executive chairman of Quidel Corporation's board of directors, André served as the company's chief executive officer from 1998 until 2001. He was chairman, president and chief executive officer of Somatogen, a bio-pharmaceuticals company, prior to its acquisition by Baxter. Before joining Somatogen, André was chairman, president and chief executive officer of Boehringer Mannheim Corporation, a global healthcare company subsequently acquired by Hoffman-La Roche. Past experience includes advisory services for Ferrer, Freeman and Company, LLC and various boards of directors. Most recently, André was a board member of NxThera as well as Nanosphere Inc., a public company in Northbrook, IL, engaged in the field of developing and commercializing molecular diagnostics for nucleic acid detection of infectious diseases. André received a B.S. in finance, economics and business from the University of Potchefstroom in South Africa.

Job Titles:

• Chief Medical Officer

Christopher Dixon, MD, joins Francis Medical as Chief Medical Officer. With over 25 years of experience as a urologist, his practice spans various clinical settings, including academia, private practice, and large hospital-based systems. Dr. Dixon brings extensive clinical investigative experience, playing pivotal roles in multiple landmark trials in urology, including the VA Cooperative Studies Program, National Institutes of Health grants, and industry-sponsored pharmaceutical and medical device trials. Since 2008, he has been integrally involved with developing water vapor ablation as a therapeutic tool, including being instrumental in developing the Rezūm™ device and conducting its pivotal trial leading to FDA approval. Dr. Dixon has consulted for Francis Medical since its inception and has been closely involved in the design and preclinical work leading to the groundbreaking therapy we have today.

Job Titles:

• Director, Solas Bioventures

Dave brings 20+ years as an angel and venture capital investor and is a founding member of Solas BioVentures, which focuses on investing in biotech and medtech companies. The cutting-edge and disruptive medical device and biotech companies Dave has led investments and served on the board of include: Francis Medical, Biostable S&E, Arrivo Bio Ventures, Nx Prenatal, Elira, Intershunt Technologies, Aegea Medical (acquired by Cooper Surgical), Veran Medical Technologies (acquired by Olympus Corporation of America), Addrenex (acquired by Sciele/Shionogi), Neuronex (acquired by Acorda), Velo Bio (acquired by AMAG Pharmaceuticals), Aerial Bio (acquired by Jazz Pharmaceuticals), NxThera (acquired by Boston Scientific), Knopp BioSciences (asset purchase by Biohaven Pharmaceutical), and Veranex. Dave is also an inventor and former C-suite operator of a medical device and pharmaceutical startup. Board-certified in Maternal-Fetal Medicine, Obstetrics and Gynecology, and Hypertension, with special expertise in Critical Care, Dave served more than 20 years as a practicing physician and as a professor and vice chairman of the Department of Obstetrics and Gynecology at the University of Tennessee College of Medicine. He earned his medical degree from the Joan C. Edwards College of Medicine at Marshall University and an MBA at The Gary W. Rollins School of Business at the University of Tennessee Chattanooga with a concentration in healthcare. He received a BS in Biology from Morehead State University, where Dave is a member of the University's Hall of Fame.

Job Titles:

• Founder and Managing Partner, Arboretum Ventures

Jan founded Arboretum Ventures on the premise that innovation is key to delivering value in healthcare, a principle she developed working in the medical device industry for over two decades. Her investments focus on promising medical technologies that enable meaningful healthcare system savings while maintaining great clinical outcomes. Jan has led and held board seats in more than a dozen investments across four funds including notable exits with HandyLab, Esperion (Nasdaq: ESPR), CardioMEMS, nVision and NxThera. Prior to co-founding Arboretum, Jan spent 20 years in entrepreneurial healthcare companies. She was previously President & Founder of Strategic Marketing Consultants advising healthcare start-ups and major medical device companies. Jan also held key management roles in marketing, clinical research, and sales for two successful medical device start-ups, Advanced Cardiovascular Systems and Devices for Vascular Intervention. Each of these companies was acquired by Eli Lilly and became the foundation for Guidant Corporation. Earlier in her career, Jan was an engineer and product manager for Procter & Gamble. Jan is currently serving as Board Chair of the National Venture Capital Association (NVCA) and has been a member of the Board of Directors since 2015. Jan has been recognized as the 2015 Crain's Newsmaker of the Year and as one of Crain's Most Influential Women in 2016. She earned a BS in Bioengineering from the University of California at Berkeley and an MBA from the Wharton School at the University of Pennsylvania.

Job Titles:

• Director of Regulatory and Quality Assurance

Joel has over 20 years of experience in medical device product and process development. Prior to joining Francis Medical, Joel held technical, management, and leadership positions in R&D, Process Development, Operations, and Regulatory and Quality Assurance at Incisive Surgical, Velocimed, and Boston Scientific. Joel holds degrees in Biology and Mechanical Engineering and is an ASQ Certified Quality Engineer, Six-Sigma Black Belt, Supplier Quality Professional, Manager of Quality / Operational Excellence, and is a TPECS Certified ISO13485 Lead Auditor.

Job Titles:

• Vice President Research, Development and Operations

Matt has extensive medical device start-up experience in roles spanning product development, marketing, strategy, and business development at companies including Ablacon, EP Map-System, Digma Medical, and NxThera. Additionally, Matt has worked as a management consultant for The Boston Consulting Group, where he advised clients in the MedTech industry. As a key member of the R&D team at NxThera from the company's early days through its acquisition by Boston Scientific, Matt developed a deep understanding of and appreciation for the power of water vapor technology to treat urological conditions. Matt earned a dual-BSE degree in Biomedical Engineering and Electrical/Computer Engineering from Duke University, an MS degree in Engineering from Harvard University, and an MBA with high distinction from Harvard Business School, where he was a George F. Baker Scholar and a Robert S. Kaplan Life Sciences Fellow.

Job Titles:

• Vice President, Finance

Michael brings over 20 years of experience in the medical device industry, primarily with startup companies. Prior to Francis Medical, he served as Vice President of Finance and Administration at NexGen Medical Systems, a Venous Thrombo-embolism technology for the treatment of Deep Vein Thrombosis. Before NexGen Medical Systems, Michael operated his own CFO/Controller consulting company supporting companies on both long-term and short-term projects, mainly in the medical device industry, over two separate periods. In between these two consulting phases Michael served as Vice President of Finance at BridgePoint Medical, a catheter-based technology to treat coronary chronic total occlusions. BridgePoint Medical was eventually acquired by Boston Scientific. Michael holds a bachelor's degree in business administration with an emphasis in accounting from the University of South Dakota and is happily married with two sons.

Job Titles:

• Chief Technology Officer
• Founder
• Company 's Founder and Chief Technology Officer

Michael founded Francis Medical in 2018 where he serves as a director and chief technology officer. Prior to founding Francis Medical, in 2008 Michael co-founded NxThera to develop and commercialize the urology applications of the vapor platform technology that he invented. Before becoming an entrepreneur, Michael taught in several departments and performed research at the University of Minnesota, including the Department of Physiology, the Department of Urologic Surgery in the School of Medicine, the Institute of Technology, and the Carlson School of Management. Professor Hoey also taught in the department of Biological Sciences at Hamline University in St. Paul, Minnesota. Michael is an expert in the interaction of thermotherapy and tissue and a prolific inventor, with 127 patents granted and 143 patents pending, the majority of which are in the medical device field. Michael's inventions include platform technologies, which are the foundation for products being sold, or in development for a variety of cardiac surgery, oncology, orthopaedics, pulmonology, general surgery, urology, gynecology, and vascular surgery applications. Michael has been a consultant to, as well as a founder/principal of, several medical products companies, which combined have raised over $250 million of capital. The formation of Francis Medical Inc. in 2018 was personal for Michael Hoey, the company's Founder and Chief Technology Officer. From growing up on a farm in southern Minnesota to teaching and researching urology disorders at the University of Minnesota, Michael has lived his life solving problems. When his father, Francis Hoey, was diagnosed with prostate cancer, Michael was faced with a problem yet to be solved. Unfortunately, after undergoing prostate cancer treatments with debilitating effects on his daily living, Francis died in 1991. Shortly after that, Michael left the University of Minnesota to develop new thermal treatment technologies that could be applied throughout the body, including the prostate. In addition to his commitment to medical research, Michael has a life-long passion for designing and building race cars. These personal and professional passions converged while Michael was testing one of his high-performance race car engines. He recognized that vaporized fuel represents a tremendous level of stored thermal energy and that this type of energy could potentially be applied to various clinical applications when using sterile water vapor, including therapies to treat prostate diseases and other urological conditions.

Job Titles:

• Vice President, Clinical Affairs

Michele brings 25 years of experience in clinical research leadership, strategy, study development, and execution. Michele previously held clinical leadership roles at both Amphora Medical and Coloplast bringing extensive experience on devices in surgical urology to Francis Medical. Additionally, she has held leadership roles at Osprey Medical and worked across several therapeutic areas while at Medtronic and the University of Minnesota Medical School. Michele received an inter-disciplinary B.S. degree in Public Health/Anthropology and a Master of Education in Organizational Leadership, Policy, and Development from the University of Minnesota.

Job Titles:

• Chief Executive Officer
• President

Mike joins Francis Medical with more than 30 years of broad healthcare marketing and sales leadership experience in medical devices, pharmaceuticals, biotechnology, clinical research, and payer economics. Prior to joining Francis Medical, Mike was the Chief Marketing Officer and Senior Vice President of International for NxThera. Prior to NxThera he was the Vice President and General Manager of the Prostate Health business unit of American Medical Systems, which developed and commercialized medical device solutions to treat BPH, prostate cancer, and stone disease. Mike received his MBA from the OPUS College of Business, University of St. Thomas in St. Paul, Minnesota and a Bachelor of Science in physics and chemistry from the University of South Dakota.

Job Titles:

• Marketing Director / Rich Hill

Rich brings over 25 years of experience in the healthcare and medical device industries. He received his MBA in Marketing from the Carlson School of Management at the University of MN and has generated proven results in a variety of impactful strategic marketing roles at Boston Scientific, American Medical Systems, ThreeWire, and Scanlan International. Rich is also a CPA and early in his career he worked in finance roles on the healthcare provider side at Southdale Pediatrics and Ridgeview Medical Center. He is passionate about utilizing his unique breadth of skills and experience to frame critical questions, acquire the relevant data, and provide actionable insights to get to the root of complex business challenges and opportunities. Rich looks forward to helping bring this more patient-friendly therapy to market as, like many of us, Rich has a father who is a prostate cancer survivor.