GLASSIA is a medicine containing human Alpha 1-Proteinase Inhibitor (Alpha 1-PI) that is used to treat adults with lung disease (emphysema) because of severe Alpha 1-antitrypsin (Alpha 1) deficiency. GLASSIA is not meant to be used as a therapy for lung disease other than severe Alpha 1 deficiency. Effects of GLASSIA on worsening lung function and emphysema progression have not been proven in clinical trials. Long-term effects of Alpha 1 replacement and maintenance therapy have not been studied.