BENGAL BIOSCIENCE

Why the Popular and Widely Sold Icariin Supplement Has No Clinical Efficacy for Erectile Dysfunction. Along with colleague Laurence V. Hicks Sr., I co-authored a paper destroying the myth that this widely popular herbal extract, Icariin, has any effect at all on the treatment of Erectile Dysfunction. For the first time ever, we showed that Icariin (in any powdered form up to 98% purity) is not soluble in water, not soluble in any alcohol, not even soluble in the main stomach acid, hydrochloric acid. Once we found a formulation that would dissolve it, we then mixed it with a penetrating cream at a high concentration for transdermal application in an informal clinical study. Icariin 98%, administered transdermally at a dosage of 500 mg, had no effect whatsoever on erectile problems in our study. Not even one of 12 volunteer subjects noted any erectogenic effect, although all had tried sildenafil in the past with positive results. We found these results disappointing, as it was postulated..

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