SIEGEL

Our goal is to live up to the classic tagline "Better Living Through Chemistry", which we achieve through computational enzyme engineering. Enzymes are the primary means by which biology performs chemical transformations. Naturally evolved enzymes have been optimized over long periods of time to address challenges biological systems face in nature. However, modern society faces additional challenges in food, energy, and health. To address these challenges, novel catalysts are needed. The Siegel lab focuses on the use of computational, genetic, and chemical methods to design, build, and test enzyme catalysts tailored for today's challenges... The Siegel Lab at UC Davis in the Genome Center researches enzymes using computational, genetic, and chemical methods to design, build, and test novel biocatalysts tailored for today's challenges