MARSHALL UNIVERSITY - Key Persons
Job Titles:
- Member of the Chair, Curriculum Committee
Job Titles:
- Director of Graduate Medical Education
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- Associate Dean for Student Affairs
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- Member of the Chair, Curriculum Committee
Job Titles:
- Member of the Chair, Curriculum Committee
- Assistant Dean of Admissions
- Associate Dean for Admissions
Job Titles:
- Member of the Chair, Curriculum Committee
- Alumni Representative
- Assistant Dean for Admissions & Student Affairs
Job Titles:
- Member of the Chair, Curriculum Committee
- Associate Dean for Faculty Advancement
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- Director
- Vice Chair of Biomedical Sciences Professor Microbiology Section Head and Co - Director, Genomics and Bioinformatics Core Facility
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- Associate Professor
- Director / Metabolic and Cellular
Research Interests
Dr. Subha Arthur's research interests are broadly focused on understanding the regulation of intestinal ion and nutrient transport processes, with emphasis on their regulation in pathophysiological states such as inflammatory bowel disease and obesity. Her primary research focus as a COBRE ACCORD investigator has been to understand the regulation of increased intestinal bile acid absorption in obesity-associated dyslipidemia by deciphering the signaling pathways and molecular mechanisms involved in the transcriptional regulation of ASBT, the primary transporter of bile acids in the intestine, in Zucker rat model of obesity as well as in a diet induced rat model, both of which are appropriate models to study obesity-associated dyslipidemia. Her research will also explore the novel regulation of ASBT at the level of the caudal-oral length of the intestine as well as along the crypt-villus axis in obesity. Her research will enable better understanding of the regulation of intestinal bile acid absorption in obesity, which may result in novel and efficacious treatment modalities for treatment of obesity-associated dyslipidemia.
Job Titles:
- Member of the Chair, Curriculum Committee
- Member of the Leadership Team
- Professor & Chair
- Vice Dean / Chair / Department
Research Interests
I was Chair of the Department of Pharmacology from 1986-2005, and when my department was merged with the Department of Physiology, I was made Chair of the combined department, a position I still hold. Over the years, I have mentored numerous undergraduate (26), graduate (40) and medical students (18), postdoctoral fellows (7) and faculty members, both within and outside my department and institution. In addition, I am the principal investigator of the NIH-funded West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE). In this capacity, I oversee a state-wide network composed primarily of new investigators at primarily undergraduate institutions across West Virginia, and serve as mentor for several of them. I have also served as a mentor for COBRE investigators at Marshall University and reviewed COBRE and other IDeA applications for NIH. Thus, I have over 30 years of experience as a mentor in many different capacities. It is also worth noting that my laboratory has been involved in translational research. One of our recent projects involves examining the pharmacogenetics of humans who died from methadone overdose. Working with medical examiner's offices in West Virginia and Kentucky, we have obtained DNA from autopsy blood cards and are examining single nucleotide polymorphisms (SNPs) in cytochrome P450s (CYPs) related to methadone metabolism as a possible explanation for the overdose deaths and as a predictive tool for preventing methadone overdose in patients taking the drug for addiction treatment or cancer pain. We are also collaborating with Dr. Monica Valentovic, Marshall University, on a project to find adjunctive treatments to prevent cisplatin nephrotoxicity and with Dr. Yi Chen, Alderson Broaddus University, to find natural products that can be used in the treatment of ovarian cancer. Lastly, as part of our work in the field of nephrotoxicity, we have examined the role of renal transporters in the accumulation of the toxicants we are studying.
Job Titles:
- Director of Physician Assistant Program
Job Titles:
- Member of the Chair, Curriculum Committee
- Chairman of Clerkship Committee
Job Titles:
- Director of Academic Information Services
Job Titles:
- Member of the Chair, Curriculum Committee
Job Titles:
- Member of the Chair, Curriculum Committee
- Associate Dean of Admissions
- Director of the Robert C. Byrd Center for Rural Health
Job Titles:
- Recruitment and Marketing Specialist
Job Titles:
- Member of the Chair, Curriculum Committee
- Interim Chief Medical Officer
- Senior Associate Dean for Clinical Affairs
Job Titles:
- Member of the Chair, Curriculum Committee
- Associate Dean for Clinical Research
Job Titles:
- Next Generation Sequencing ( NGS ) Manager
Job Titles:
- Chairman
- Member of the Chair, Curriculum Committee
Job Titles:
- Member of the Chair, Curriculum Committee
- Associate Dean for Diversity
Job Titles:
- Member of the Chair, Curriculum Committee
- Director of Development & Alumni Affairs
- Executive Director / Assistant Director of Development & Alumni
- Student Wellness Center
The Linda S. Holmes Student Wellness Center provides a safe, convenient study and relaxation space for medical students. The center also houses the medical school's student affairs and financial aid offices.
Job Titles:
- Member of the Chair, Curriculum Committee
- Associate Dean for Academic Affairs
Job Titles:
- Member of the Chair, Curriculum Committee
- Senior Associate Dean for Physician Collaboration & Student Engagement
Job Titles:
- Chief Information Officer
Job Titles:
- Associate Dean for Continuing Medical Education
Job Titles:
- Member of the Chair, Curriculum Committee
- Assistant Dean for Assessment & Evaluation
- Assistant Dean of Assessment
- Chairman of Pre - Clerkship Committee
Job Titles:
- Executive Secretary
- Associate Dean for Medical Education
Job Titles:
- Member of the Chair, Curriculum Committee
- Director of Medical Education
- Neurology
Job Titles:
- Member of the Chair, Curriculum Committee
Job Titles:
- Assistant
- Assistant Dean
- Associate Professor
- Director
Research Interests
I have a varied interest in research with four major research areas. These areas all focus on endothelial cell function and tissue barriers. Though my initial studies focused on transport, my current interest is how health care issues common in Appalachia (Diabetes, hypertension substance abuse) regulate brain endothelial function and what role this plays in psychiatric disorders. My studies have been funded via federal grants at both the PPG and RO1 level. This research has resulted in 43 publications with Pubmed IDs, three other research publications, four book chapters, and one book as an editor, as well as numerous abstracts to scientific conferences.
Richard Egleton, PhD
Assistant Dean of the Office of Research and Graduate Education, Associate Professor, Research Cluster Coordinator
(304) 696-3523
egleton@marshall.edu
Job Titles:
- Chief Medical Information Officer
Job Titles:
- Member of the Chair, Curriculum Committee
- Associate Dean for Diversity & Inclusion
Job Titles:
- Family & Community Health
Job Titles:
- Member of the Chair, Curriculum Committee
- Registrar
- Registrar & Academic Affairs Coordinator
Job Titles:
- Director of Clinical Training / Department of Psychiatry & Behavioral Medicine
Job Titles:
- Member of the Chair, Curriculum Committee
Job Titles:
- Member of the Leadership Team
- Director / Appalachian Clinical & Translational Science Institute
- Vice Dean / Chair / Department
Job Titles:
- Director
- Member of the Chair, Curriculum Committee
- Assistant Dean for Clinical Research
Job Titles:
- Director
- Director of the Flow Cytometry Core, Associate Professor